中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [54]
大连化学物理研究所 [27]
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期刊论文 [222]
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浏览/检索结果:
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PROTAC Prodrug-Integrated Nanosensitizer for Potentiating Radiation Therapy of Cancer
期刊论文
OAI收割
ADVANCED MATERIALS, 2024, 页码: 12
作者:
Zhang, Shunan
;
Lai, Yi
;
Pan, Jiaxing
;
Saeed, Madiha
;
Li, Shiqin
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/04/09
active tumor targeting
nanosensitizer
PROTAC prodrug
radiation therapy
tumor microenvironment
Structure-based identification of new orally bioavailable BRD9-PROTACs for treating acute myelocytic leukemia
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 262, 页码: 18
作者:
Zhang, Jingyu
;
Duan, Haiting
;
Gui, Renzhao
;
Wu, Mingfei
;
Shen, Liteng
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/12/19
Acute myeloid leukemia
Bromodomain-containing protein 9
Proteolysis-targeting chimera
Orally bioavailable
Docking
HDAC3 and HDAC8 PROTAC dual degrader reveals roles of histone acetylation in gene regulation
期刊论文
OAI收割
CELL CHEMICAL BIOLOGY, 2023, 卷号: 30, 期号: 11, 页码: 1421-+
作者:
Xiao, Yufeng
;
Hale, Seth
;
Awasthee, Nikee
;
Meng, Chengcheng
;
Zhang, Xuan
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/01/16
Genome-wide association study of hippocampal blood-oxygen-level-dependent-cerebral blood flow correlation in Chinese Han population
期刊论文
OAI收割
ISCIENCE, 2023, 卷号: 26, 期号: 10, 页码: 16
作者:
Xue, Hui
;
Xu, Xiaojun
;
Yan, Zhihan
;
Cheng, Jingliang
;
Zhang, Longjiang
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/11/29
Potential Involvement of DNA Methylation in Hybrid Sterility in Hermaphroditic Argopecten Scallops
期刊论文
OAI收割
MARINE BIOTECHNOLOGY, 2023, 页码: 17
作者:
Yu, Tieying
;
Ning, Junhao
;
Chen, Min
;
Wang, Fukai
;
Liu, Guilong
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/01/26
Hermaphroditic Argopecten scallops
Hybrid sterility
DNA methylation
Oogenesis
ROS
ATP
Investigation of targets and anticancer mechanisms of covalently acting natural products by functional proteomics
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 卷号: 44, 期号: 8, 页码: 1701-1711
作者:
Zhao, Wen-si
;
Chen, Kai-feng
;
Liu, Man
;
Jia, Xing-long
;
Huang, Yu-qi
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/03/27
natural products
proteomics
ABPP
eriocalyxin B
parthenolide
Recent Advances in Pro-PROTAC Development to Address On-Target Off-Tumor Toxicity
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 13
作者:
Chen, Chuanjie
;
Yang, Yiwen
;
Wang, Zhe
;
Li, Huiwen
;
Dong, Chanjuan
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/10/17
Stimuli-activatable PROTACs for precise protein degradation and cancer therapy
期刊论文
OAI收割
SCIENCE BULLETIN, 2023, 卷号: 68, 期号: 10, 页码: 1069-1085
作者:
Gao, Jing
;
Yang, Lei
;
Lei, Shumin
;
Zhou, Feng
;
Nie, Huijun
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/10/17
PROTAC
Stimuli-activatable prodrug
Precise protein degradation
Nanomedicine
Combinatory therapy
Unraveling the catalytic mechanism of SARS-CoV-2 papain-like protease with allosteric modulation of C270 mutation using multiscale computational approaches
期刊论文
OAI收割
CHEMICAL SCIENCE, 2023, 卷号: 14, 期号: 18, 页码: 4681-4696
作者:
Shao, Qiang
;
Xiong, Muya
;
Li, Jiameng
;
Hu, Hangchen
;
Su, Haixia
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/03/27
Discovery of a Potent, Cooperative, and Selective SOS1 PROTAC ZZ151 with In Vivo Antitumor Efficacy in KRAS-Mutant Cancers
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 6, 页码: 4197-4214
作者:
Zhou, Zehui
;
Zhou, Guizhen
;
Zhou, Chuan
;
Fan, Zisheng
;
Cui, Rongrong
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/03/27