中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [43]
西北高原生物研究所 [10]
中国科学院大学 [4]
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期刊论文 [73]
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2,2 ',4,4 '-Tetrabromodiphenyl Ether (PBDE 47) Selectively Stimulates Proatherogenic PPAR gamma Signatures in Human THP-1 Macrophages to Contribute to Foam Cell Formation
期刊论文
OAI收割
CHEMICAL RESEARCH IN TOXICOLOGY, 2022, 卷号: 35, 期号: 6, 页码: 1023-1035
作者:
Ren, Qidong
;
Xie, Xinni
;
Zhao, Chuanfang
;
Wen, Qing
;
Pan, Ruiying
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2022/11/08
ACTIVATED-RECEPTOR-GAMMA
BROMINATED FLAME RETARDANTS
ACID-BINDING PROTEIN
GENE-EXPRESSION
LIGAND-BINDING
DIPHENYL ETHERS
INDOOR DUST
EXPOSURE
CD36
ACCUMULATION
Combined treatment with FABP4 inhibitor ameliorates rosiglitazone-induced liver steatosis in obese diabetic db/db mice
期刊论文
OAI收割
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2021, 页码: 10
作者:
Chen, Meng-Ting
;
Huang, Jun-Shang
;
Gao, Ding-Ding
;
Li, Ying-Xia
;
Wang, He-Yao
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2021/08/17
combined treatment
FABP4 inhibitor
liver steatosis
obese type 2 diabetes
rosiglitazone
Identification and structural insight of an effective PPAR gamma modulator with improved therapeutic index for anti-diabetic drug discovery
期刊论文
OAI收割
CHEMICAL SCIENCE, 2020, 卷号: 11, 期号: 8, 页码: 2260-2268
作者:
Jiang, Haowen
;
Zhou, X. Edward
;
Shi, Jingjing
;
Zhou, Zhi
;
Zhao, Guanguan
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/07/01
Bis(2-ethylhexyl)-2,3,4,5-tetrabromophthalate Affects Lipid Metabolism in Zebrafish Larvae via DNA Methylation Modification
期刊论文
OAI收割
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2020, 卷号: 54, 期号: 1, 页码: 355-363
作者:
Guo, Wei
;
Hang, Jian
;
Wu, Shengmin
;
Shi, Xiongjie
;
Wang, Qiangwei
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2020/05/13
Delta FosB regulates rosiglitazone-induced milk fat synthesis and cell survival
期刊论文
OAI收割
JOURNAL OF CELLULAR PHYSIOLOGY, 2018, 卷号: 233, 期号: 12
作者:
Wei, Xuefeng
;
Li, Hui
;
Zhao, Guangwei
;
Yang, Jiameng
;
Li, Lihui
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2019/11/26
FosB
apoptosis
milk fat synthesis
MMP-9
rosiglitazone
Modulation of glucose metabolism by a natural compound from Chloranthus japonicus via activation of AMP-activated protein kinase
期刊论文
OAI收割
SCIENTIFIC REPORTS, 2017, 卷号: 7, 页码: 778
作者:
Hu, Rongkuan
;
Yan, Huan
;
Fei, Xiaoyan
;
Liu, Haiyang
;
Wu, Jiarui
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2017/06/01
Identification of a novel selective PPAR gamma ligand with a unique binding mode and improved therapeutic profile in vitro
期刊论文
OAI收割
Scientific Reports, 2017, 卷号: 7
作者:
Yi, Wei
;
Shi, Jingjing
;
Zhao, Guanguan
;
Zhou, X. Edward
;
Suino-Powell, Kelly
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
Ppar gamma is regulated by mir-27b-3p negatively and plays an important role in porcine oocyte maturation
期刊论文
iSwitch采集
Biochemical and biophysical research communications, 2016, 卷号: 479, 期号: 2, 页码: 224-230
作者:
Song, Chunlei
;
Yao, Jing
;
Cao, Chunwei
;
Liang, Xiaojuan
;
Huang, Jiaojiao
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2019/05/09
Pig
Mirna
Oocyte maturation
Ppar gamma
Fatty acid metabolism
Bavachinin, as a novel natural pan-PPAR agonist, exhibits unique synergistic effects with synthetic PPAR-gamma and PPAR-alpha agonists on carbohydrate and lipid metabolism in db/db and diet-induced obese mice
期刊论文
OAI收割
DIABETOLOGIA, 2016, 卷号: 59, 期号: 6, 页码: 1276-1286
作者:
Feng, Li
;
Luo, Huan
;
Xu, Zhijian
;
Yang, Zhuo
;
Du, Guoxin
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2016/08/22
Alternative binding site
Bavachinin
Canonical ligand-binding pocket
Carbohydrate metabolism
Lipid metabolism
Pan-PPAR agonist
Synergistic effects
Bavachinin, as a novel natural pan-PPAR agonist, exhibits unique synergistic effects with synthetic PPAR-gamma and PPAR-alpha agonists on carbohydrate and lipid metabolism in db/db and diet-induced obese mice
期刊论文
OAI收割
DIABETOLOGIA, 2016, 卷号: 59, 期号: 6, 页码: 1276-1286
作者:
Feng, Li
;
Luo, Huan
;
Xu, Zhijian
;
Yang, Zhuo
;
Du, Guoxin
  |  
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2019/01/08
Alternative binding site
Bavachinin
Canonical ligand-binding pocket
Carbohydrate metabolism
Lipid metabolism
Pan-PPAR agonist
Synergistic effects