中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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Design, Synthesis, and Biological Evaluation of Potent and Selective PROTAC Degraders of Oncogenic KRAS
G12D
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 2, 页码: 1147-1167
作者:
Zhou, Chuan
;
Fan, Zisheng
;
Gu, Yuejiao
;
Ge, Zhiming
;
Tao, Zhaofan
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/02/27
JE-133 Suppresses LPS-Induced Neuroinflammation Associated with the Regulation of JAK/STAT and Nrf2 Signaling Pathways
期刊论文
OAI收割
ACS CHEMICAL NEUROSCIENCE, 2024, 卷号: 15, 期号: 2, 页码: 258-267
作者:
Tao, Lingxue
;
Yu, Weichen
;
Liu, Ziyi
;
Zhao, Danfeng
;
Lin, Sijin
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2024/02/27
neuroinflammation
microglia
LPS
JAK/STAT
Nrf2
Role of F-box proteins in human upper gastrointestinal tumors
期刊论文
OAI收割
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 2024, 卷号: 1879, 期号: 1, 页码: 16
作者:
Zhang, Che
;
Pan, Guangzhao
;
Qin, Jiang-Jiang
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2024/02/27
F-box protein
Upper gastrointestinal cancer
E3 ubiquitin ligase
Ubiquitin
Nardostachys jatamansi and levodopa combination alleviates Parkinson's disease symptoms in rats through activation of Nrf2 and inhibition of NLRP3 signaling pathways
期刊论文
OAI收割
PHARMACEUTICAL BIOLOGY, 2023, 卷号: 61, 期号: 1, 页码: 1175-1185
作者:
Li, Jiayuan
;
Yu, Jiahe
;
Guo, Jianyou
;
Liu, Jinfeng
;
Wan, Guohui
  |  
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2023/10/09
Dyskinesia
neurotransmitters
dopaminergic neurons
nardosinone
molecular docking
oxidative stress
neuroinflammation
>
Direct mechanical exposure initiates hepatocyte proliferation
期刊论文
OAI收割
JHEP REPORTS, 2023, 卷号: 5, 期号: 12, 页码: 13
作者:
Li, Wang
;
Wu Y(武亿)
;
Hu, Wenhui
;
Zhou J(周瑾)
;
Shu XY(舒芯钰)
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/01/02
Mechanotransduction
FAK
hepatic sinusoid chip
Synthesis, evaluation and molecular dynamics study of human toll-like receptor 2/6 specific monoacyl lipopeptides as candidate immunostimulants
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 141, 页码: 17
作者:
Zhu, Yueyue
;
Liu, Bo
;
Chen, Zonglong
;
Wang, Xianyang
;
Wang, Yujie
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/12/08
Toll -like receptor 2/6 agonists
PamCS
Structure-activity relationship
Lipopeptide
Immunostimulants
Berberine derivative DCZ0358 induce oxidative damage by ROS-mediated JNK signaling in DLBCL cells
期刊论文
OAI收割
INTERNATIONAL IMMUNOPHARMACOLOGY, 2023, 卷号: 125, 页码: 15
作者:
Feng, Qilin
;
Hu, Ke
;
Hu, Huifang
;
Lu, Yumeng
;
Zhang, Hui
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2024/01/16
DLBCL
ROS
DNA damage
JNK
Mitochondrial dysfunction
Radiomic signatures reveal multiscale intratumor heterogeneity associated with tissue tolerance and survival in re-irradiated nasopharyngeal carcinoma: a multicenter study
期刊论文
OAI收割
BMC MEDICINE, 2023, 卷号: 21, 期号: 1, 页码: 13
作者:
Liu, Ting
;
Dong, Di
;
Zhao, Xun
;
Ou, Xiao-Min
;
Yi, Jun-Lin
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/02/22
Recurrent nasopharyngeal carcinoma
Re-radiotherapy
Nasopharyngeal necrosis
Radiomics
Atractylone in the
Atractylodes macrocephala
Rhizoma Essential Oil and Its Anti-Inflammatory Activity
期刊论文
OAI收割
MOLECULES, 2023, 卷号: 28, 期号: 21, 页码: 15
作者:
Li, Ling
;
He, Yihao
;
Wang, Nan
;
Li, Yuting
;
Du, Yaoyao
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2023/12/19
Atractylodes macrocephala rhizoma essential oil
atractylone
signaling pathway
anti-inflammation
antioxidative stress
intestinal injury reduction
Stress can affect mitochondrial energy metabolism and AMPK/SIRT1 signaling pathway in rats
期刊论文
OAI收割
BRAIN RESEARCH BULLETIN, 2023, 卷号: 203, 页码: 9
作者:
Zhao, An-ran
;
Li, Jie
;
Wang, Si-qi
;
Bian, Li-hua
;
Li, Wen-jing
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2023/11/29
Anxiety
Mitochondrial function
Energy metabolism
AMPK/SIRT1 pathways