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浏览/检索结果: 共77条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Discovery of novel triazine derivatives as potent retinoic acid receptor-related orphan receptor gamma t (ROR gamma t) inverse agonists 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 256, 页码: 18 作者:  Lu, Lixue;  Chen, Song;  Yu, Mingcheng;  Zhou, Ronghui;  Guo, Siqi   |  收藏  |  浏览/下载：14/0  |  提交时间：2023/10/17 ROR gamma t  Triazines  Inverse agonist  Psoriasis  Autoimmune diseases   Structure-based discovery of potent USP28 inhibitors derived from Vismodegib 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 254, 页码: 15 作者:  Zhou, Di;  Xu, Zhuo;  Huang, Yaodong;  Wang, Hui;  Zhu, Xiaoli   |  收藏  |  浏览/下载：21/0  |  提交时间：2023/10/17 USP28  Structure-based  Vismodegib derivatives  Structure-activity relationships  c-Myc   Design, synthesis and biological evaluation of KRASG12C-PROTACs 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 78, 页码: 14 作者:  Zhang, Xiaoyi;  Zhao, Tong;  Sun, Minghao;  Li, Pei;  Lai, Mengzhen   |  收藏  |  浏览/下载：13/0  |  提交时间：2023/04/10 KRASG12C  PROTAC  Covalent inhibitors  Structure-activity relationships (SARs)  Anticancer   Identification of 1H-pyrazolo[3,4-b]pyridine derivatives as novel and potent TBK1 inhibitors: design, synthesis, biological evaluation, and molecular docking study 期刊论文  OAI收割 JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2022, 卷号: 37, 期号: 1, 页码: 1411-1425 作者:  Sun, Yin;  Tang, Haotian;  Wang, Xiaoyan;  Feng, Fang;  Fan, Tiantian   |  收藏  |  浏览/下载：36/0  |  提交时间：2022/08/16 TBK1 inhibitors  1H-pyrazolo[3  4-b]pyridine  structure-activity relationships (SARs)  immune response  cancer therapy   Development and structure–activity relationships of tanshinones as selective 11β-hydroxysteroid dehydrogenase 1 inhibitors 期刊论文  OAI收割 Natural Products and Bioprospecting, 2022, 卷号: 12, 期号: 1 作者:  Deng,Xu;  Huang,Su-Ling;  Ren,Jian;  Pan,Zheng-Hong;  Shen,Yu   |  收藏  |  浏览/下载：29/0  |  提交时间：2022/11/11 Metabolic syndrome  Tanshinones  Selective 11β-HSD1 inhibitors  Structure–activity relationships   Development and structure-activity relationships of tanshinones as selective 11beta-hydroxysteroid dehydrogenase 1 inhibitors 期刊论文  OAI收割 Natural products and bioprospecting, 2022, 卷号: 12, 期号: 1, 页码: 36 作者:  Deng, Xu;  Huang, Su-Ling;  Ren, Jian;  Pan, Zheng-Hong;  Shen, Yu   |  收藏  |  浏览/下载：8/0  |  提交时间：2024/03/15 Metabolic syndrome  Selective 11beta-HSD1 inhibitors  Structure-activity relationships  Tanshinones   Insight into Thermodynamic and Kinetic Profiles in Small-Molecule Optimization 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 16, 页码: 10809-10847 作者:  Liu, Wei;  Jiang, Jingsheng;  Lin, Yating;  You, Qidong;  Wang, Lei   |  收藏  |  浏览/下载：18/0  |  提交时间：2022/11/11 Synthesis and Biochemical Evaluation of 8H-Indeno[1,2-d]thiazole Derivatives as Novel SARS-CoV-2 3CL Protease Inhibitors 期刊论文  OAI收割 MOLECULES, 2022, 卷号: 27, 期号: 10, 页码: 11 作者:  Wu, Jing;  Feng, Bo;  Gao, Li-Xin;  Zhang, Chun;  Li, Jia   |  收藏  |  浏览/下载：24/0  |  提交时间：2022/08/16 COVID-19  M-pro inhibitors  drug design and synthesis  structure-activity relationships (SAR)   Synthesis and Biological Activities of Dihydrooxazolo[5,4-d]- pyrrolo[1,2-a]pyrimidinones 期刊论文  OAI收割 CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2022, 卷号: 42, 期号: 2, 页码: 543-556 作者:  Zeng, Y (Zeng Yan) [1] , [2];  Nie, LF (Nie Lifei) [1];  Niu, C (Niu Chao) [1];  Mamatjan, A (Mamatjan Aytilla) [1] , [2];  Bozorov, K (Bozorov Khurshed) [1]   |  收藏  |  浏览/下载：60/0  |  提交时间：2022/05/17 oxazopyrimidinone  synthesis  bioisosterism  anticancer activity  antimicrobial activity  structure-activity relationships (SARs)   Development and structure-activity relationships of tanshinones as selective 11β-hydroxysteroid dehydrogenase 1 inhibitors 期刊论文  OAI收割 NATURAL PRODUCTS AND BIOPROSPECTING, 2022, 卷号: 12, 期号: 6, 页码: 1 作者:  Deng Xu;  Huang Suling;  Ren Jian;  Pan Zhenghong;  Shen Yu   |  收藏  |  浏览/下载：7/0  |  提交时间：2023/05/22 Metabolic syndrome  Tanshinones  Selective 11β-HSD1 inhibitors  Structure-activity relationships