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浏览/检索结果: 共463条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 The Tyrosine Kinase Inhibitor Bafetinib Inhibits PAR2-induced Activation of TRPV4 In Vitro and Pain In Vivo1 期刊论文  OAI收割 出版物, 2111, 页码: 1-44 作者:  1M S Grace;  T Lieu;  B Darby;  F C Abogadie;  N Veldhuis N W Bunnett;  P McIntyre   |  收藏  |  浏览/下载：218/0  |  提交时间：2017/07/24 Transient Receptor Potential Ion Channel  Trpv4  Protease Activated Receptor  Par2  Pain  Tyrosine Kinase  Bafetinib   Discovery of a 1,6-naphthyridin-4-one-based AXL inhibitor with improved pharmacokinetics and enhanced in vivo antitumor efficacy 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 17 作者:  Lan, Yaohan;  Peng, Xia;  Ji, Yinchun;  Su, Yi;  Duan, Wenhu   |  收藏  |  浏览/下载：7/0  |  提交时间：2024/02/27 AXL inhibitor  In vivo antitumor efficacy  6-Naphthyridin-4-one derivatives  Scaffold hopping  Structure-based drug design   Structure-based drug discovery of novel fused- pyrazolone carboxamide derivatives as potent and selective AXL inhibitors 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4918-4933 作者:  Fang, Feifei;  Dai, Yang;  Wang, Hao;  Ji, Yinchun;  Liang, Xuewu   |  收藏  |  浏览/下载：6/0  |  提交时间：2024/01/26 derivatives  Antitumor drug development  Potential AXL inhibitor  Antitumor activity  Structure-based drug design  Fused-pyrazolone carboxamide   A neural cell adhesion molecule from oyster Crassostrea gigas: Molecular identification and immune functional characterization 期刊论文  OAI收割 INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2023, 卷号: 247, 页码: 13 作者:  Qiao, Xue;  Liu, Conghui;  Wang, Weilin;  Yang, Chuanyan;  Li, Meijia   |  收藏  |  浏览/下载：4/0  |  提交时间：2023/12/13 IgCAM  Neural cell adhesion molecule  PRR  Phagocytosis   Design, synthesis and pharmacological evaluation of 2,3-dihydrobenzo-furan IRAK4 inhibitors for the treatment of diffuse large B-cell lymphoma 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 256, 页码: 16 作者:  Chen, Yun;  Ning, Yi;  Chen, Zhiwei;  Xue, Yaping;  Wu, Qingyun   |  收藏  |  浏览/下载：9/0  |  提交时间：2023/10/17 Apoptosis  Diffuse large B-Cell lymphoma  Interleukin-1 receptor associated kinase 4  Structure-based drug design  2  3-Dihydrobenzofuran   创伤后应激障碍与抑郁共病的通路分析和基因多态性分析 学位论文  OAI收割 中国科学院心理研究所: 中国科学院大学, 2023 作者:  张静怡   |  收藏  |  浏览/下载：17/0  |  提交时间：2023/08/31 PTSD  抑郁  共病基因  生物学通路分析   Design, synthesis, and evaluation of pyrido.[3,4-b]pyrazin-2(1H)-one derivatives as potent FLT3 inhibitors 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 79, 页码: 117155 作者:  Sun, Mei;  Wang, Chang;  Wang, Peipei;  Ye, Qingqing;  Zhou, Yubo   |  收藏  |  浏览/下载：0/0  |  提交时间：2024/04/09 FLT3  FLT3-D835Y  Acute myeloid leukemia  Structure -activity relationships   AXL antibody and AXL-ADC mediate antitumor efficacy via targeting AXL in tumor-intrinsic epithelial-mesenchymal transition and tumor-associated M2-like macrophage 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2023, 页码: 14 作者:  Pei, Jin-peng;  Wang, Yue;  Ma, Lan-ping;  Wang, Xin;  Liu, Liang   |  收藏  |  浏览/下载：20/0  |  提交时间：2023/04/10 AXL  NSCLC  TNBC  M2-macrophage  antibody-drug conjugate   Targeting CSF-1R represents an effective strategy in modulating inflammatory diseases 期刊论文  OAI收割 PHARMACOLOGICAL RESEARCH, 2023, 卷号: 187, 页码: 17 作者:  Xiang, Caigui   |  收藏  |  浏览/下载：18/0  |  提交时间：2023/04/10 CSF-1R  CSF-1  IL-34  Inflammatory diseases  Myeloid cells   Discovery of HCD3514 as a potent EGFR inhibitor against C797S mutation in vitro and in vivo 期刊论文  OAI收割 JOURNAL OF CANCER, 2023, 卷号: 14, 期号: 1, 页码: 152-162 作者:  Lai, Mengzhen;  Zhang, Tao;  Chen, Hao;  Song, Peiran;  Tong, Linjiang   |  收藏  |  浏览/下载：79/0  |  提交时间：2023/04/10 fourth-generation EGFR inhibitor  EGFRC797S mutation  NSCLC  drug resistance  small molecular inhibitor