中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [78]
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Editorial: The 3Ds of marine viruses: discovery, diversity, and dynamics
期刊论文
OAI收割
FRONTIERS IN MARINE SCIENCE, 2023, 卷号: 10, 页码: 2
作者:
Umberto, Rosani
;
Liu, Zhaoqun
;
Chen, Hao
;
Liu, Qin
;
Xin, Lusheng
  |  
收藏
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浏览/下载:0/0
  |  
提交时间:2024/04/07
marine viruses
viral disease
biogeochemical processes
evolution
host-virus
Interaction
Structure-based development and preclinical evaluation of the SARS-CoV-2 3C-like protease inhibitor simnotrelvir
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 15
作者:
Jiang, Xiangrui
;
Su, Haixia
;
Shang, Weijuan
;
Zhou, Feng
;
Zhang, Yan
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/03/25
A prodrug of the capsid assembly modulator improved druggability and lowing HBsAg and HBeAg for the treatment of chronic hepatitis B
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 257, 页码: 8
作者:
Chen, Wuhong
;
Gong, Ying
;
Long, Guozhang
;
Wang, Xinran
;
Yang, Yurong
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2023/10/17
HBV
Capsid assembly modulators
Prodrug
Hepatitis B surface antigen
Discovery of (S)-N-(2-Amino-4-fluorophenyl)-4-(1-(3-(4-((dimethylamino)methyl)phenyl)-6-oxopyridazin-1(6H)-yl)ethyl)benzamide as Potent Class I Selective HDAC Inhibitor for Oral Anticancer Drug Candidate
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 10, 页码: 7016-7037
作者:
Li, Daqiang
;
Zhang, Zhuo
;
Li, Yalei
;
Wang, Xinyi
;
Zhong, Hanyue
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2023/10/17
Discovery, synthesis and mechanism study of 2,3,5-substituted [1,2,4]-thiadiazoles as covalent inhibitors targeting 3C-Like protease of SARS-CoV-2
期刊论文
OAI收割
European journal of medicinal chemistry, 2023, 卷号: 249, 页码: 115129
作者:
Ren, Pengxuan
;
Yu, Changyue
;
Zhang, Ruxue
;
Nie, Tianqing
;
Hu, Qiaoyu
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/03/26
Extracellular vesicles mediate antibody-resistant transmission of SARS-CoV-2
期刊论文
OAI收割
CELL DISCOVERY, 2023, 卷号: 9, 期号: 1, 页码: 15
作者:
Xia, Bingqing
;
Pan, Xiaoyan
;
Luo, Rong-Hua
;
Shen, Xurui
;
Li, Shuangqu
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2023/04/10
Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma
期刊论文
OAI收割
NATURE METABOLISM, 2023, 页码: 35
作者:
Yang, Zijian
;
Yan, Cong
;
Ma, Jiaqiang
;
Peng, Panpan
;
Ren, Xuelian
  |  
收藏
  |  
浏览/下载:18/0
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提交时间:2023/04/10
Multiplication of defective Ebola virus in a complementary permissive cell line
期刊论文
OAI收割
ANTIVIRAL RESEARCH, 2023, 卷号: 209, 页码: 8
作者:
Tong, Xian-Kun
;
Li, Heng
;
Yang, Li
;
Xie, Shi-Zhe
;
Xie, Sha
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2023/04/10
Predicting In Vitro and In Vivo Anti-SARS-CoV-2 Activities of Antivirals by Intracellular Bioavailability and Biochemical Activity
期刊论文
OAI收割
ACS OMEGA, 2022, 页码: 13
作者:
Zhang, Jinwen
;
He, Mingfeng
;
Xie, Qian
;
Su, Ailing
;
Yang, Kuangyang
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收藏
  |  
浏览/下载:14/0
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提交时间:2023/04/10
Design, synthesis and biological evaluation of novel dihydrobenzodioxine derivatives as HBV capsid protein inhibitors
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2022, 卷号: 128, 页码: 12
作者:
Liu, Linyue
;
Li, Chuanju
;
Xie, Yong
;
Zhang, Lei
;
Chen, Yunfu
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/10/17
HBV
Capsid protein inhibitors
Pharmacophore hybrid
Scaffold hopping
HepAD38 cells