中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [12]
采集方式
OAI收割 [12]
内容类型
期刊论文 [12]
发表日期
2023 [1]
2016 [1]
2014 [3]
2013 [2]
2012 [1]
2011 [3]
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专题:上海药物研究所
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Simultaneous quantification of 3 ',4 '-dimethoxy flavonol-3-O-glucoside and its major metabolite in human plasma by LC-MS/MS and its application to a clinical pharmacokinetic study
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2023, 卷号: 225, 页码: 9
作者:
Wang, Lu
;
Shen, Haifeng
;
Zhan, Yan
;
Zhang, Yifan
;
Zhang, Yong
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2023/04/10
3?4?-Dimethoxy flavonol-3-O-glucoside
Aglycone glucuronide
LC-MS
MS
Human pharmacokinetic study
Design, Synthesis, and Biological Evaluation of Novel Tetrahydroprotoberberine Derivatives (THPBs) as Selective alpha(1A)-Adrenoceptor Antagonists
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 59, 期号: 20, 页码: 9489-9502
作者:
Guo, Diliang
;
Li, Jing
;
Lin, Henry
;
Zhou, Yu
;
Chen, Ying
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/01/08
Small molecule compound induces chromatin de-condensation and facilitates induced pluripotent stem cell generation
期刊论文
OAI收割
JOURNAL OF MOLECULAR CELL BIOLOGY, 2014, 卷号: 6, 期号: 5, 页码: 409-420
作者:
Wei, Xiaoyuan
;
Chen, Yueting
;
Xu, Yongyu
;
Zhan, Yang
;
Zhang, Ru
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2019/01/08
induced pluripotent stem cells
reprogramming
CYT296
small molecule compound
chromatin de-condensation
chromatin remodeling
HP1 alpha
Blocking autocrine VEGF signaling by sunitinib, an anti-cancer drug, promotes embryonic stem cell self-renewal and somatic cell reprogramming
期刊论文
OAI收割
CELL RESEARCH, 2014, 卷号: 24, 期号: 9, 页码: 1121-1136
作者:
Chen, Guofang
;
Xu, Xinxiu
;
Zhang, Lihong
;
Fu, Yanbin
;
Wang, Min
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
sunitinib
Sutent
embryonic stem cell
self-renewal
iPSC
VEGF
autocrine
blockingautocrinevegfsignalingbysunitinibananticancerdrugpromotesembryonicstemcellselfrenewalandsomaticcellreprogramming
期刊论文
OAI收割
cellresearch, 2014, 卷号: 24, 期号: 9, 页码: 1121
作者:
Chen Guofang
;
Xu Xinxiu
;
Zhang Lihong
;
Fu Yanbin
;
Wang Min
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/07/01
ENDOPLASMIC-RETICULUM STRESS
GROWTH-FACTOR RECEPTORS
TUMOR-CELLS
FACTOR-I
DIFFERENTIATION
EXPRESSION
HYPOXIA
ANGIOGENESIS
HIF-1-ALPHA
INHIBITOR
sunitinib
Sutent
embryonic stem cell
self-renewal
iPSC
VEGF
autocrine
The gating charge pathway of an epilepsy-associated potassium channel accommodates chemical ligands
期刊论文
OAI收割
CELL RESEARCH, 2013, 卷号: 23, 期号: 9, 页码: 1106-1118
作者:
Li, Ping
;
Chen, Zhuxi
;
Xu, Haiyan
;
Sun, Haifeng
;
Li, Hao
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/01/08
voltage-gated potassium channel
gating charge pathway
KCNQ2 activator
binding site
anti-epilepsy drug
Asymmetric total synthesis and identification of tetrahydroprotoberberine derivatives as new antipsychotic agents possessing a dopamine D-1, D-2 and serotonin 5-HT1A multi-action profile
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2013, 卷号: 21, 期号: 4, 页码: 856-868
作者:
Sun, Haifeng
;
Zhu, Liyuan
;
Yang, Huicui
;
Qian, Wangke
;
Guo, Lin
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/01/08
Asymmetric synthesis
Tetrahydroprotoberberines
Dopamine receptors
Serotonin receptors
Multi-action
New pharmacological profile
An expedient Pd/DBU mediated cyanation of aryl/heteroaryl bromides with K-4[Fe(CN)(6)]
期刊论文
OAI收割
CHEMICAL COMMUNICATIONS, 2012, 卷号: 48, 期号: 23, 页码: 2909-2911
作者:
Zhang, Dengyou
;
Sun, Haifeng
;
Zhang, Lei
;
Zhou, Yu
;
Li, Chunpu
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
Lithium, an anti-psychotic drug, greatly enhances the generation of induced pluripotent stem cells
期刊论文
OAI收割
CELL RESEARCH, 2011, 卷号: 21, 期号: 10, 页码: 1424-1435
作者:
Wang, Quan
;
Xu, Xinxiu
;
Li, Jun
;
Liu, Jing
;
Gu, Haifeng
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/01/08
lithium
induced pluripotent stem cells
iPS
GSK3 beta
Nanog
LSD1
histone demethylase
Synthesis of 4-Aryl-2(5H)-furanones by Gold(I)-Catalyzed Intramolecular Annulation
期刊论文
OAI收割
ADVANCED SYNTHESIS & CATALYSIS, 2011, 卷号: 353, 期号: 9, 页码: 1413-1419
作者:
Sun, Haifeng
;
Huang, He
;
Zhang, Dengyou
;
Feng, Enguang
;
Qian, Wangke
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/01/08
4-aryl-2(5H)-furanones
gold(I) catalysts
intramolecular annulations
prop-2-ynyl 3-oxo-3-phenylpropanoates