中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [49]
采集方式
OAI收割 [49]
内容类型
期刊论文 [46]
会议论文 [3]
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2024 [1]
2023 [2]
2022 [2]
2021 [5]
2020 [4]
2019 [5]
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专题:上海药物研究所
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DRAK2 suppresses autophagy by phosphorylating ULK1 at Ser
56
to diminish pancreatic β cell function upon overnutrition
期刊论文
OAI收割
SCIENCE TRANSLATIONAL MEDICINE, 2024, 卷号: 16, 期号: 733, 页码: 16
作者:
Lu, Yuting
;
Xu, Junyu
;
Li, Yufeng
;
Wang, Ruoran
;
Dai, Chengqiu
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/03/13
Structure-Based Ligand Discovery Targeting the Transmembrane Domain of Frizzled Receptor FZD7
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 14
作者:
Li, Cuixia
;
Wu, Yiran
;
Wang, Wenli
;
Xu, Lu
;
Zhou, Yan
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2023/10/17
Luteolin Protects Pancreatic beta Cells against Apoptosis through Regulation of Autophagy and ROS Clearance
期刊论文
OAI收割
PHARMACEUTICALS, 2023, 卷号: 16, 期号: 7, 页码: 17
作者:
Han, Ming
;
Lu, Yuting
;
Tao, Yunhua
;
Zhang, Xinwen
;
Dai, Chengqiu
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2023/10/17
luteolin
type 2 diabetes
beta cell
autophagy
reactive oxygen species
Discovery and characterization of a novel cGAS covalent inhibitor for the treatment of inflammatory bowel disease
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 10
作者:
Song, Jia
;
Yang, Rui-rui
;
Chang, Jie
;
Liu, Ya-dan
;
Lu, Cheng-hao
  |  
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2022/11/11
cyclic GMP-AMP synthase
covalent inhibitor
inflammatory bowel disease
high-throughput screening
Engineered nanomedicines block the PD-1/PD-L1 axis for potentiated cancer immunotherapy
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 10
作者:
Li, Jun-hao
;
Huang, Lu-jia
;
Zhou, Hui-ling
;
Shan, Yi-ming
;
Chen, Fang-min
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2022/08/16
cancer immunotherapy
immune checkpoint blockade
PD-1/PD-L1 axis
nanomedicine
nanosized drug delivery systems
The methyltransferase METTL3 negatively regulates nonalcoholic steatohepatitis (NASH) progression
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 17
作者:
Li, Xinzhi
;
Yuan, Bingchuan
;
Lu, Min
;
Wang, Yuqin
;
Ding, Na
  |  
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2022/01/18
CsCCD2 Access Tunnel Design for a Broader Substrate Profile in Crocetin Production
期刊论文
OAI收割
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2021, 卷号: 69, 期号: 39, 页码: 11626-11636
作者:
Liang, Nan
;
Yao, Ming-Dong
;
Wang, Ying
;
Liu, Jia
;
Feng, Lu
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2021/12/01
crocetin
CCD2
access tunnel engineering
Saccharomyces cerevisiae
Affinity Mass Spectrometry-Based Fragment Screening Identified a New Negative Allosteric Modulator of the Adenosine A(2A) Receptor Targeting the Sodium Ion Pocket
期刊论文
OAI收割
ACS CHEMICAL BIOLOGY, 2021, 卷号: 16, 期号: 6, 页码: 991-1002
作者:
Lu, Yan
;
Liu, Hongyue
;
Yang, Dehua
;
Zhong, Li
;
Xin, Ye
  |  
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2021/08/17
Activating Adenosine Monophosphate-Activated Protein Kinase Mediates Fibroblast Growth Factor 1 Protection From Nonalcoholic Fatty Liver Disease in Mice
期刊论文
OAI收割
HEPATOLOGY, 2021, 卷号: 73, 期号: 6, 页码: 2206-2222
作者:
Lin, Qian
;
Huang, Zhifeng
;
Cai, Genxiang
;
Fan, Xia
;
Yan, Xiaoqing
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2021/08/17
Aristolochic acid I promoted clonal expansion but did not induce hepatocellular carcinoma in adult rats
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 12
作者:
Liu, Yong-zhen
;
Lu, Heng-lei
;
Qi, Xin-ming
;
Xing, Guo-zhen
;
Wang, Xin
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/05/24
aristolochic acid I
glutathione S-transferase placental form-positive foci
clonal expansion
hepatocellular carcinoma
medium-term rat liver bioassay
DNA adducts