中国科学院机构知识库网格系统: 检索

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	Discovery and characterization of a novel highly potent and selective type II native and drug-resistant V299L mutant BCR-ABL inhibitor (CHMFL-ABL-039) for Chronic Myeloid Leukemia (CML) 期刊论文 OAI收割 CANCER BIOLOGY & THERAPY, 2019, 卷号: 20, 期号: 6, 页码: 877-885 作者: Wu, Jiaxin; Wang, Aoli; Li, Xixiang; Chen, Cheng; Qi, Ziping \| 收藏 \| 浏览/下载：76/0 \| 提交时间：2019/11/27 BCR-ABL PDGFR chronic myeloid leukemia kinase inhibitor
	Discovery of 2-(4-Chloro-3-(trifluoromethyl)phenyl)-N-(4-((6,7-dimethoxyquinolin-4-yl)oxy)phenyl)acetamide (CHMFL-KIT-64) as a Novel Orally Available Potent Inhibitor against Broad-Spectrum Mutants of 期刊论文 OAI收割 J. Med. Chem., 2019 作者: Yun Wu; Beilei Wang; Junjie Wang; Qi S(亓爽); Fengming Zou \| 收藏 \| 浏览/下载：42/0 \| 提交时间：2020/10/20
	Discovery of N-(4-(6-Acetamidopyrimidin-4-yloxy)phenyl)-2-(2-(trifluoromethyl)phenyl)acetamide (CHMFL-FLT3-335) as a Potent FMS-like Tyrosine Kinase 3 Internal Tandem Duplication (FLT3-ITD) Mutant Selective Inhibitor for Acute Myeloid Leukemia 期刊论文 OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 2, 页码: 875-892 作者: Liang, Xiaofei; Wang, Beilei; Chen, Cheng; Wang, Aoli; Hu, Chen \| 收藏 \| 浏览/下载：34/0 \| 提交时间：2020/05/21
	p53-dependent upregulation of miR-16-2 by sanguinarine induces cell cycle arrest and apoptosis in hepatocellular carcinoma 期刊论文 OAI收割 CANCER LETTERS, 2019, 卷号: 459, 页码: 50-58 作者: Zhang, Beilei; Wang, Xinan; Deng, Jiacong; Zheng, Haifeng; Liu, Wei \| 收藏 \| 浏览/下载：38/0 \| 提交时间：2019/12/16 miRNA-16 p53 Sanguinarine Cell cycle Apoptosis
	Repurposing cabozantinib to GISTs: Overcoming multiple imatinib-resistant cKIT mutations including gatekeeper and activation loop mutants in GISTs preclinical models 期刊论文 OAI收割 CANCER LETTERS, 2019, 页码: 105-114 作者: Lu, Tingting; Chen, Cheng; Wang, Aoli; Jiang, Zongru; Qi, Ziping \| 收藏 \| 浏览/下载：32/0 \| 提交时间：2020/07/14 cKIT T670I mutant Activation loop mutants Drug resistance