中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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  • 上海药物研究所 [40]
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A propolis-derived small molecule ameliorates metabolic syndrome in obese mice by targeting the CREB/CRTC2 transcriptional complex 期刊论文  OAI收割
NATURE COMMUNICATIONS, 2022, 卷号: 13, 期号: 1, 页码: 20
作者:  
Chen, Yaqiong;  Wang, Jiang;  Wang, Yibing;  Wang, Pengfei;  Zhou, Zan
  |  收藏  |  浏览/下载:29/0  |  提交时间:2022/06/15
The triterpenoid sapogenin (2 alpha-OH-Protopanoxadiol) ameliorates metabolic syndrome via the intestinal FXR/GLP-1 axis through gut microbiota remodelling 期刊论文  OAI收割
CELL DEATH & DISEASE, 2020, 卷号: 11, 期号: 9, 页码: 10
作者:  
Xie, Zhifu;  Jiang, Haowen;  Liu, Wei;  Zhang, Xinwen;  Chen, Dakai
  |  收藏  |  浏览/下载:33/0  |  提交时间:2020/12/21
Disrupting phosphatase SHP2 in macrophages protects mice from high-fat diet-induced hepatic steatosis and insulin resistance by elevating IL-18 levels 期刊论文  OAI收割
JOURNAL OF BIOLOGICAL CHEMISTRY, 2020, 卷号: 295, 期号: 31, 页码: 10842-10856
作者:  
Liu, Wen;  Yin, Ye;  Wang, Meijing;  Fan, Ting;  Zhu, Yuyu
  |  收藏  |  浏览/下载:86/0  |  提交时间:2020/12/24
Design, synthesis and biological evaluation of vincamine derivatives as potential pancreatic beta-cells protective agents for the treatment of type 2 diabetes mellitus 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 188, 页码: 17
作者:  
Wang, Junwei;  Lv, Xue;  Xu, Jiawen;  Liu, Xinpeng;  Du, Te
  |  收藏  |  浏览/下载:24/0  |  提交时间:2020/07/01
TGF-beta 1/p65/MAT2A pathway regulates liver fibrogenesis via intracellular SAM 期刊论文  OAI收割
EBIOMEDICINE, 2019, 卷号: 42, 页码: 458-469
作者:  
Wang, Kuifeng;  Fang, Shanhua;  Liu, Qian;  Gao, Jing;  Wang, Xiaoning
  |  收藏  |  浏览/下载:25/0  |  提交时间:2020/07/01
Synthetic derivatives of the natural product 13-amino 2-desoxy-4-epi-pulchellin inhibit STAT3 signaling and induce G2/M arrest and death of colon cancer cells 期刊论文  OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 6, 页码: 782-785
作者:  
Niu, Junxing;  Huang, Hui;  Wang, Fei;  Zhang, Xianjing;  Liu, Yi
  |  收藏  |  浏览/下载:14/0  |  提交时间:2020/07/01
Vincamine as a GPR40 agonist improves glucose homeostasis in type 2 diabetic mice 期刊论文  OAI收割
JOURNAL OF ENDOCRINOLOGY, 2019, 卷号: 240, 期号: 2, 页码: 195-214
作者:  
Du, Te;  Yang, Liu;  Xu, Xu;  Shi, Xiaofan;  Xu, Xin
  |  收藏  |  浏览/下载:102/0  |  提交时间:2019/01/08
A Thermally Robust La3Si6N11:Ce-in-Glass Film for High-Brightness Blue-Laser-Driven Solid State Lighting 期刊论文  OAI收割
LASER & PHOTONICS REVIEWS, 2019, 卷号: 13, 期号: 2, 页码: 10
作者:  
You, Shihai;  Li, Shuxing;  Zheng, Peng;  Zhou, Tianliang;  Wang, Le
  |  收藏  |  浏览/下载:17/0  |  提交时间:2020/07/01
A 20(S)-protopanaxadiol derivative PPD12 reverses ABCB1-mediated multidrug resistance with oral bioavailability and low toxicity 期刊论文  OAI收割
ONCOLOGY LETTERS, 2018, 卷号: 16, 期号: 5, 页码: 5891-5899
作者:  
Wei, Shunfeng;  Chen, Wantao;  Hu, Lihong;  Pan, Jinsong;  Wang, Xu
  |  收藏  |  浏览/下载:82/0  |  提交时间:2019/01/08
A natural compound derivative P-13 inhibits STAT3 signaling by covalently inhibiting Janus kinase 2 期刊论文  OAI收割
Investigational new drugs, 2018
作者:  
Huang, Hui;  Niu, Junxing;  Wang, Fei;  Hu, Lihong;  Yu, Qiang
  |  收藏  |  浏览/下载:26/0  |  提交时间:2019/01/08