机构

• 上海药物研究所 [187]

采集方式

• OAI收割 [187]

内容类型

• 期刊论文 [185]
• 会议论文 [2]

发表日期

• 2024 [5]
• 2023 [18]
• 2022 [20]
• 2021 [22]
• 2020 [18]
• 2019 [12]
• 更多

学科主题

• Pharmacolo... [2]
• Chemistry [1]
• Plant Scie... [1]

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浏览/检索结果: 共187条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 DRAK2 suppresses autophagy by phosphorylating ULK1 at Ser56 to diminish pancreatic β cell function upon overnutrition 期刊论文  OAI收割 SCIENCE TRANSLATIONAL MEDICINE, 2024, 卷号: 16, 期号: 733, 页码: 16 作者:  Lu, Yuting;  Xu, Junyu;  Li, Yufeng;  Wang, Ruoran;  Dai, Chengqiu   |  收藏  |  浏览/下载：17/0  |  提交时间：2024/03/13 Nanobodies as negative allosteric modulators for human calcium sensing receptor 期刊论文  OAI收割 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2024, 卷号: 695, 页码: 9 作者:  Cui, Qianqian;  Wang, Lu;  Wang, Haonan;  Chen, Xiaochen;  Han, Li   |  收藏  |  浏览/下载：16/0  |  提交时间：2024/04/09 G-protein-coupled receptor  Extracellular calcium sensing receptor  Nanobody  Cryo-electron microscope  Systemic Ca 2+homoeostasis   Discovery and exploration of novel somatostatin receptor subtype 5 (SSTR5) antagonists for the treatment of cholesterol gallstones 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 264, 页码: 16 作者:  Han, Fanghui;  Zhao, Tingting;  Zhang, Yanglong;  Yun, Ying;  Xu, Yuanyuan   |  收藏  |  浏览/下载：3/0  |  提交时间：2024/02/19 SSTR5 antagonist  Gallbladder emptying  Cholesterol gallstones   D3Rings: A Fast and Accurate Method for Ring System Identification and Deep Generation of Drug-Like Cyclic Compounds 期刊论文  OAI收割 JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2024, 卷号: 64, 期号: 3, 页码: 724-736 作者:  Ma, Minfei;  Zhang, Xinben;  Zhou, Liping;  Han, Zijian;  Shi, Yulong   |  收藏  |  浏览/下载：19/0  |  提交时间：2024/03/13 Dimeric cation-cation aggregates stabilized by 2Ch-2N chalcogen bonds: Crystallographic and theoretical evidences 期刊论文  OAI收割 CHEMICAL PHYSICS, 2024, 卷号: 576, 页码: 10 作者:  Liu, Na;  Han, Zijian;  Lu, Yunxiang;  Xu, Zhijian;  Zhu, Weiliang   |  收藏  |  浏览/下载：7/0  |  提交时间：2023/12/11 2Ch-2N chalcogen bonds  Homocations  Solvents  Evidences   Original Research Response to programmed cell death protein 1 antibody in patients with Epstein-Barr virus-associated intrahepatic cholangiocarcinoma 期刊论文  OAI收割 EUROPEAN JOURNAL OF CANCER, 2023, 卷号: 194, 页码: 9 作者:  He, Wen-Zhuo;  Huang, Yu-Hua;  Hu, Wan-Ming;  Wang, Fang;  Xu, Yu-Xia   |  收藏  |  浏览/下载：10/0  |  提交时间：2023/12/11 Epstein-Barr virus  Intrahepatic cholangiocarcinoma  Programmed cell death protein 1  Immunotherapy   AhR-STAT3-HO-1/COX-2 signalling pathway may restrict ferroptosis and improve hMSC accumulation and efficacy in mouse liver 期刊论文  OAI收割 BRITISH JOURNAL OF PHARMACOLOGY, 2023, 页码: 17 作者:  Han, Li;  Ma, Chenhui;  Wu, Zhitao;  Xu, Huiming;  Li, Hai   |  收藏  |  浏览/下载：7/0  |  提交时间：2023/12/08 aryl hydrocarbon receptor  ferroptosis  iron  ischaemia/reperfusion liver injury  liver disease  mesenchymal stem cells   Discovery of ARD-1676 as a Highly Potent and Orally Efficacious AR PROTAC Degrader with a Broad Activity against AR Mutants for the Treatment of AR plus Human Prostate Cancer 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 18, 页码: 13280-13303 作者:  Xiang, Weiguo;  Zhao, Lijie;  Han, Xin;  Xu, Tianfeng;  Kregel, Steven   |  收藏  |  浏览/下载：9/0  |  提交时间：2023/12/08 D3CARP: a comprehensive platform with multiple-conformation based docking, ligand similarity search and deep learning approaches for target prediction and virtual screening 期刊论文  OAI收割 COMPUTERS IN BIOLOGY AND MEDICINE, 2023, 卷号: 164, 页码: 8 作者:  Shi, Yulong;  Zhang, Xinben;  Yang, Yanqing;  Cai, Tingting;  Peng, Cheng   |  收藏  |  浏览/下载：21/0  |  提交时间：2023/10/17 Target prediction  Virtual screening  Molecular docking  Ligand similarity search  Deep learning   Design, synthesis and biological evaluation of salicylanilides as novel allosteric inhibitors of human pancreatic lipase 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 91, 页码: 11 作者:  Zhao, Yitian;  Zhang, Min;  Hou, Xudong;  Han, Jiaxin;  Qin, Xiaoya   |  收藏  |  浏览/下载：12/0  |  提交时间：2023/10/17 Salicylanilide  hPL inhibitor  Structure -activity relationship  Anti -obesity