机构

• 上海药物研究所 [550]

采集方式

• OAI收割 [550]

内容类型

• 期刊论文 [548]
• 会议论文 [2]

发表日期

• 2024 [3]
• 2023 [44]
• 2022 [55]
• 2021 [69]
• 2020 [44]
• 2019 [32]
• 更多

学科主题

• Chemistry [1]
• Pharmacolo... [1]

筛选

浏览/检索结果: 共550条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Development and Validation of an ADA-Tolerant Assay for Quantification of an Exatecan-Based ADC in Monkey Plasma 期刊论文  OAI收割 MOLECULES, 2024, 卷号: 29, 期号: 3, 页码: 14 作者:  Tao, Yimin;  Lu, Wei;  Gao, Jinli;  Yang, Shuangshuang;  Ruan, Chaoyi   |  收藏  |  浏览/下载：13/0  |  提交时间：2024/03/13 antibody-drug conjugate (ADC)  bioanalysis  anti-drug antibody (ADA)  ligand binding assay (LBA)  ADA-tolerant assay   Design, Synthesis, and Biological Evaluation of Potent and Selective PROTAC Degraders of Oncogenic KRASG12D 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 2, 页码: 1147-1167 作者:  Zhou, Chuan;  Fan, Zisheng;  Gu, Yuejiao;  Ge, Zhiming;  Tao, Zhaofan   |  收藏  |  浏览/下载：8/0  |  提交时间：2024/02/27 Structure-Guided Design, Synthesis, and Antivirulence Assessment of Covalent Staphylococcus aureus Sortase A Inhibitors 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 2, 页码: 1127-1146 作者:  Yue, Chuan;  Yuan, Ziqi;  Xu, Guobin;  Guan, Xiang-Na;  Wei, Bingyan   |  收藏  |  浏览/下载：4/0  |  提交时间：2024/02/27 Single-cell RNA sequencing reveals a hierarchical transcriptional regulatory network of terpenoid biosynthesis in cotton secretory glandular cells 期刊论文  OAI收割 MOLECULAR PLANT, 2023, 卷号: 16, 期号: 12, 页码: 1990-2003 作者:  Lin, Jia-Ling;  Chen, Longxian;  Wu, Wen-Kai;  Guo, Xiao-Xiang;  Yu, Cheng-Hui   |  收藏  |  浏览/下载：10/0  |  提交时间：2024/01/26 A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects 期刊论文  OAI收割 EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 卷号: 191, 页码: 9 作者:  Yang, Xin-Mei;  Yang, Yang;  Yao, Bu-Fan;  Ye, Pan-Pan;  Xu, Yan   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/12/11 COVID-19  Simnotrelvir  Safety  Pharmacokinetics  Healthy subjects   C-terminal modification and functionalization of proteins via a self-cleavage tag triggered by a small molecule 期刊论文  OAI收割 NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 13 作者:  Zeng, Yue;  Shi, Wei;  Liu, Zhi;  Xu, Hao;  Liu, Liya   |  收藏  |  浏览/下载：4/0  |  提交时间：2024/02/19 Design, synthesis of auristatins-glucuronide conjugates targeting the β-glucuronidase in tumor microenvironment 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2023, 卷号: 95, 页码: 5 作者:  Wang, Yujie;  Xu, Keshi;  Liu, Hongchun;  Zhang, Wei;  Hu, Chun   |  收藏  |  浏览/下载：4/0  |  提交时间：2023/12/19 Auristatin E  beta-Glucuronidase  Antiproliferation  Tumor microenvironment   Two new compounds from the Hainan Soft Corals Sinularia tumulosa and Sinularia depressa with their anti-inflammatory or cytotoxic activities 期刊论文  OAI收割 JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2023, 卷号: 25, 期号: 10, 页码: 949-956 作者:  Xu, Ting;  Yu, Dan-Dan;  Su, Ming-Zhi;  Yao, Li-Gong;  Li, Song-Wei   |  收藏  |  浏览/下载：1/0  |  提交时间：2024/03/27 Sinularia  marine natural product  anti-inflammatory activity  cytotoxicity   Characterization of ginsenosides from Panax japonicus var. major (Zhu-Zi-Shen) based on ultra-high performance liquid chromatography/quadrupole time-of-flight mass spectrometry and desorption electrospray ionization-mass spectrometry imaging 期刊论文  OAI收割 CHINESE MEDICINE, 2023, 卷号: 18, 期号: 1, 页码: 14 作者:  Jiang, Meiting;  Li, Xiaohang;  Zhao, Yuying;  Zou, Yadan;  Bai, Maoli   |  收藏  |  浏览/下载：6/0  |  提交时间：2023/12/08 Panax japonicus var. major  Ginsenoside  UHPLC/QTOF-MS  DESI-MSI  Precursor ions list  Spatial distribution   Degradation of Cyclin-Dependent Kinase 9/Cyclin T1 by Optimized Microtubule-Associated Protein 1 Light Chain 3 Beta-Recruiting Coumarin Analogs 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 17 作者:  Zeng, Yanping;  Xiao, Jian;  Xu, Yuanxin;  Wei, Fan;  Tian, Lina   |  收藏  |  浏览/下载：7/0  |  提交时间：2023/10/17