中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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  • 上海药物研究所 [48]
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DZ2002 alleviates corneal angiogenesis and inflammation in rodent models of dry eye disease via regulating STAT3-PI3KAkt-NF-kappa B pathway 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 14
作者:  
Wu, Chun-mei;  Mao, Jia-wen;  Zhu, Jin-zhi;  Xie, Can-can;  Yao, Jia-ying
  |  收藏  |  浏览/下载:13/0  |  提交时间:2023/10/17
Prime editing-based gene correction alleviates the hyperexcitable phenotype and seizures of a genetic epilepsy mouse model 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 4
作者:  
Cao, Bi-rong;  Huang, Yi-ming;  Tian, Fu-yun;  Li, Jin-hui;  Xu, Chun-long
  |  收藏  |  浏览/下载:26/0  |  提交时间:2023/10/17
Thioparib inhibits homologous recombination repair, activates the type I IFN response, and overcomes olaparib resistance 期刊论文  OAI收割
EMBO MOLECULAR MEDICINE, 2023, 页码: 24
作者:  
Wang, Li-Min;  Wang, Pingyuan;  Chen, Xiao-Min;  Yang, Hui;  Song, Shan-Shan
  |  收藏  |  浏览/下载:21/0  |  提交时间:2023/04/10
Twin drug design, synthesis and evaluation of diosgenin derivatives as multitargeted agents for the treatment of vascular dementia 期刊论文  OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 37, 页码: 16
作者:  
Yang, Gui-Xiang;  Sun, Jia-Min;  Zheng, Lu-Lu;  Zhang, Li;  Li, Jie
  |  收藏  |  浏览/下载:23/0  |  提交时间:2021/06/11
Downregulation of c-Myc expression confers sensitivity to CHK1 inhibitors in hematologic malignancies 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:  
Jiang, Kai-long;  Tong, Le-xian;  Wang, Tao;  Wang, Han-lin;  Hu, Xiao-bei
  |  收藏  |  浏览/下载:48/0  |  提交时间:2021/05/24
Mitochondrial Uncoupling Coordinated With PDH Activation Safely Ameliorates Hyperglycemia via Promoting Glucose Oxidation 期刊论文  OAI收割
DIABETES, 2019, 卷号: 68, 期号: 12, 页码: 2197-2209
作者:  
Jiang, Haowen;  Jin, Jia;  Duan, Yanan;  Xie, Zhifu;  Li, Yufeng
  |  收藏  |  浏览/下载:31/0  |  提交时间:2020/07/01
Integrating yeast chemical genomics and mammalian cell pathway analysis 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 9, 页码: 1245-1255
作者:  
Zhou, Fu-lai;  Li, Sheena C.;  Zhu, Yue;  Guo, Wan-jing;  Shao, Li-jun
  |  收藏  |  浏览/下载:22/0  |  提交时间:2020/07/01
Development of Small-Molecules Targeting Receptor Activator of Nuclear Factor-kappa B Ligand (RANKL)-Receptor Activator of Nuclear Factor-kappa B (RANK) Protein-Protein Interaction by Structure-Based Virtual Screening and Hit Optimization 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 11, 页码: 5370-5381
作者:  
Jiang, Min;  Peng, Lei;  Yang, Kai;  Wang, Tianqi;  Yan, Xueming
  |  收藏  |  浏览/下载:17/0  |  提交时间:2020/07/01
PPh3/I-2/HCOOH: An efficient CO source for the synthesis of phthalimides 期刊论文  OAI收割
TETRAHEDRON, 2019, 卷号: 75, 期号: 9, 页码: 1180-1185
作者:  
Wang, Yingying;  Zhou, Yang;  Lei, Min;  Hou, Jinjun;  Jin, Qinghao
  |  收藏  |  浏览/下载:19/0  |  提交时间:2020/07/01
A Novel Rhein Derivative Modulates Bone Formation and Resorption and Ameliorates Estrogen-Dependent Bone Loss 期刊论文  OAI收割
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2018
作者:  
Jiang, Min;  Wang, Tianqi;  Yan, Xueming;  Liu, Zhuochao;  Yan, Yufei
  |  收藏  |  浏览/下载:94/0  |  提交时间:2019/01/08