中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [48]
采集方式
OAI收割 [48]
内容类型
期刊论文 [48]
发表日期
2023 [3]
2021 [2]
2019 [4]
2018 [1]
2017 [3]
2016 [6]
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浏览/检索结果:
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专题:上海药物研究所
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DZ2002 alleviates corneal angiogenesis and inflammation in rodent models of dry eye disease via regulating STAT3-PI3KAkt-NF-kappa B pathway
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 14
作者:
Wu, Chun-mei
;
Mao, Jia-wen
;
Zhu, Jin-zhi
;
Xie, Can-can
;
Yao, Jia-ying
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2023/10/17
dry eye disease
DZ2002
corneal angiogenesis
immunomodulatory function
NF-kappa B
ophthalmic therapy
Prime editing-based gene correction alleviates the hyperexcitable phenotype and seizures of a genetic epilepsy mouse model
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 4
作者:
Cao, Bi-rong
;
Huang, Yi-ming
;
Tian, Fu-yun
;
Li, Jin-hui
;
Xu, Chun-long
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2023/10/17
Thioparib inhibits homologous recombination repair, activates the type I IFN response, and overcomes olaparib resistance
期刊论文
OAI收割
EMBO MOLECULAR MEDICINE, 2023, 页码: 24
作者:
Wang, Li-Min
;
Wang, Pingyuan
;
Chen, Xiao-Min
;
Yang, Hui
;
Song, Shan-Shan
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2023/04/10
homologous recombination repair
olaparib-resistant
PARP inhibitor
PARP7
type I interferons
Twin drug design, synthesis and evaluation of diosgenin derivatives as multitargeted agents for the treatment of vascular dementia
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 37, 页码: 16
作者:
Yang, Gui-Xiang
;
Sun, Jia-Min
;
Zheng, Lu-Lu
;
Zhang, Li
;
Li, Jie
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2021/06/11
Vascular dementia
Diosgenin
Antioxidant
Anti-cholinesterase
Multi-target-directed ligands
Downregulation of c-Myc expression confers sensitivity to CHK1 inhibitors in hematologic malignancies
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:
Jiang, Kai-long
;
Tong, Le-xian
;
Wang, Tao
;
Wang, Han-lin
;
Hu, Xiao-bei
  |  
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2021/05/24
CHK1 inhibitors
PY34
drug sensitivity
c-Myc
hematologic malignancies
Mitochondrial Uncoupling Coordinated With PDH Activation Safely Ameliorates Hyperglycemia via Promoting Glucose Oxidation
期刊论文
OAI收割
DIABETES, 2019, 卷号: 68, 期号: 12, 页码: 2197-2209
作者:
Jiang, Haowen
;
Jin, Jia
;
Duan, Yanan
;
Xie, Zhifu
;
Li, Yufeng
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/07/01
Integrating yeast chemical genomics and mammalian cell pathway analysis
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 9, 页码: 1245-1255
作者:
Zhou, Fu-lai
;
Li, Sheena C.
;
Zhu, Yue
;
Guo, Wan-jing
;
Shao, Li-jun
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/07/01
yeast
chemical genomics
tubulin cytoskeleton assembly
autophagy
Wnt/beta-catenin signaling pathway
Development of Small-Molecules Targeting Receptor Activator of Nuclear Factor-kappa B Ligand (RANKL)-Receptor Activator of Nuclear Factor-kappa B (RANK) Protein-Protein Interaction by Structure-Based Virtual Screening and Hit Optimization
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 11, 页码: 5370-5381
作者:
Jiang, Min
;
Peng, Lei
;
Yang, Kai
;
Wang, Tianqi
;
Yan, Xueming
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2020/07/01
PPh3/I-2/HCOOH: An efficient CO source for the synthesis of phthalimides
期刊论文
OAI收割
TETRAHEDRON, 2019, 卷号: 75, 期号: 9, 页码: 1180-1185
作者:
Wang, Yingying
;
Zhou, Yang
;
Lei, Min
;
Hou, Jinjun
;
Jin, Qinghao
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2020/07/01
Phthalimide
PPh3/I-2/HCOOH
2-lodobenzamide
Pd(OAc)(2)
CO source
A Novel Rhein Derivative Modulates Bone Formation and Resorption and Ameliorates Estrogen-Dependent Bone Loss
期刊论文
OAI收割
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2018
作者:
Jiang, Min
;
Wang, Tianqi
;
Yan, Xueming
;
Liu, Zhuochao
;
Yan, Yufei
  |  
收藏
  |  
浏览/下载:94/0
  |  
提交时间:2019/01/08