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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [378]
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OAI收割 [378]
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期刊论文 [369]
会议论文 [9]
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2024 [3]
2023 [31]
2022 [37]
2021 [29]
2020 [22]
2019 [24]
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Biochemist... [1]
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浏览/检索结果:
共378条,第1-10条
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专题:上海药物研究所
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In vitro inhibition of six active sesquiterpenoids in zedoary turmeric oil on human liver cytochrome P450 enzymes
期刊论文
OAI收割
JOURNAL OF ETHNOPHARMACOLOGY, 2024, 卷号: 322, 页码: 10
作者:
Liu, Suyan
;
Zhao, Yong
;
Tang, Xuan
;
Yang, Junling
;
Pan, Chen
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/02/27
Sesquiterpenoids
Inhibition
CYP450s
Drug-drug interactions
Mechanism
Blocking tumor-platelet crosstalk to prevent tumor metastasis via reprograming glycolysis using biomimetic membrane-hybridized liposomes
期刊论文
OAI收割
JOURNAL OF CONTROLLED RELEASE, 2024, 卷号: 366, 页码: 328-341
作者:
Zhu, Jie
;
Wang, Rui
;
Yang, Chenxiao
;
Shao, Xinyue
;
Zhang, Yi
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2024/03/06
Platelet
Circulating tumor cells (CTCs)
Glycolysis
Metastasis
Hybrid-membrane liposome
Quercetin
Shikonin
Pharmacologically significant constituents collectively responsible for anti-sepsis action of XueBiJing, a Chinese herb-based intravenous formulation
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 16
作者:
Cheng, Chen
;
Ren, Chao
;
Li, Mu-zi
;
Liu, Yi-hui
;
Yao, Ren-qi
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/02/27
Traditional Chinese medicine
XueBiJing
sepsis
mortality
pharmacokinetic compatibility
polypharmacology
A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects
期刊论文
OAI收割
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 卷号: 191, 页码: 9
作者:
Yang, Xin-Mei
;
Yang, Yang
;
Yao, Bu-Fan
;
Ye, Pan-Pan
;
Xu, Yan
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/12/11
COVID-19
Simnotrelvir
Safety
Pharmacokinetics
Healthy subjects
Preclinical and early clinical studies of a novel compound SYHA1813 that efficiently crosses the blood-brain barrier and exhibits potent activity against glioblastoma
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4748-4764
作者:
Liu, Yingqiang
;
Zhan, Zhengsheng
;
Kang, Zhuang
;
Li, Mengyuan
;
Lv, Yongcong
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/01/26
Small molecule inhibitor
Tumor microenvironment
Immune-checkpoint
immune-deficient mouse models
including temozolomide (TMZ) insensitive tumors. Notably
Identification of [1,2,4]Triazolo[4,3-a]pyrazine PARP1 inhibitors with overcome acquired resistance activities
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 259, 页码: 19
作者:
Wang, Pingyuan
;
Zhu, Wen-Ting
;
Wang, Yajing
;
Song, Shan-Shan
;
Xi, Yong
  |  
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2023/10/17
PARP1 inhibitor
Synthetic lethality
Drug resistance
Anticancer
Structure -activity relationship
Original Research Response to programmed cell death protein 1 antibody in patients with Epstein-Barr virus-associated intrahepatic cholangiocarcinoma
期刊论文
OAI收割
EUROPEAN JOURNAL OF CANCER, 2023, 卷号: 194, 页码: 9
作者:
He, Wen-Zhuo
;
Huang, Yu-Hua
;
Hu, Wan-Ming
;
Wang, Fang
;
Xu, Yu-Xia
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/12/11
Epstein-Barr virus
Intrahepatic cholangiocarcinoma
Programmed cell death protein 1
Immunotherapy
Molecular basis of ClC-6 function and its impairment in human disease
期刊论文
OAI收割
SCIENCE ADVANCES, 2023, 卷号: 9, 期号: 41, 页码: 15
作者:
Zhang, Bing
;
Zhang, Sensen
;
Polovitskaya, Maya M.
;
Yi, Jingbo
;
Ye, Binglu
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/12/08
Anxiolytic effect of antidiabetic metformin is mediated by AMPK activation in mPFC inhibitory neurons
期刊论文
OAI收割
MOLECULAR PSYCHIATRY, 2023, 页码: 11
作者:
Zhang, Yong-mei
;
Zong, Hai-chao
;
Qi, Ying-bei
;
Chang, Liu-liu
;
Gao, Ya-nan
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/12/08
Addition of a-synuclein aggregates to the intestinal environment recapitulates Parkinsonian symptoms in model systems
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 16
作者:
Yang, Ze-xian
;
Zhang, Yu
;
Wang, Qing
;
Zhang, Lei
;
Liu, Yi-fei
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/12/08
Parkinson's disease
gut-brain axis
a-Synuclein
inflammation
microbiota
intestinal mouse coloclysis model