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Discovery of a 1,6-naphthyridin-4-one-based AXL inhibitor with improved pharmacokinetics and enhanced in vivo antitumor efficacy
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 17
作者:
Lan, Yaohan
;
Peng, Xia
;
Ji, Yinchun
;
Su, Yi
;
Duan, Wenhu
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/02/27
AXL inhibitor
In vivo antitumor efficacy
6-Naphthyridin-4-one derivatives
Scaffold hopping
Structure-based drug design
Discovery, Optimization, and Evaluation of Novel Pyridin-2(1
H
)-one Analogues as Potent TRK Inhibitors for Cancer Treatment
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 2, 页码: 1168-1183
作者:
Xu, Zichao
;
Peng, Xia
;
Zhang, Renjie
;
Ji, Yinchun
;
You, Mengke
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/02/27
Proteogenomic characterization of small cell lung cancer identifies biological insights and subtype-specific therapeutic strategies
期刊论文
OAI收割
CELL, 2024, 卷号: 187, 期号: 1, 页码: 49
作者:
Liu, Qian
;
Zhang, Jing
;
Guo, Chenchen
;
Wang, Mengcheng
;
Wang, Chenfei
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/02/27
Structure-based drug discovery of novel fused- pyrazolone carboxamide derivatives as potent and selective AXL inhibitors
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4918-4933
作者:
Fang, Feifei
;
Dai, Yang
;
Wang, Hao
;
Ji, Yinchun
;
Liang, Xuewu
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/01/26
derivatives
Antitumor drug development
Potential AXL inhibitor
Antitumor activity
Structure-based drug design
Fused-pyrazolone carboxamide
Spatial patterns and recent temporal trends in global transpiration modelled using eco-evolutionary optimality
期刊论文
OAI收割
AGRICULTURAL AND FOREST METEOROLOGY, 2023, 卷号: 342, 页码: 11
作者:
Li, Shijie
;
Wang, Guojie
;
Zhu, Chenxia
;
Hannemann, Marco
;
Poyatos, Rafael
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/03/01
Transpiration
Penman -Monteith
Ball-Berry-Leuning model
P model
Precipitation and vegetation transpiration variations dominate the dynamics of agricultural drought characteristics in China
期刊论文
OAI收割
SCIENCE OF THE TOTAL ENVIRONMENT, 2023, 卷号: 898, 页码: 12
作者:
Guo, Wenwen
;
Huang, Shengzhi
;
Huang, Qiang
;
She, Dunxian
;
Shi, Haiyun
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/10/09
Editor
Christian Herrera
Agricultural drought
Drought events
Drought dynamics
Driving factors
China
Hyodeoxycholic acid alleviates non-alcoholic fatty liver disease through modulating the gut-liver axis
期刊论文
OAI收割
CELL METABOLISM, 2023, 卷号: 35, 期号: 10, 页码: 1752-+
作者:
Kuang, Junliang
;
Wang, Jieyi
;
Li, Yitao
;
Li, Mengci
;
Zhao, Mingliang
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2023/12/08
Back to Business: SLX 1746–331 after 13 Years of Silence
期刊论文
OAI收割
The Astrophysical Journal, 2023, 卷号: 955, 期号: 2, 页码: 10
作者:
Peng, Jing-Qiang
;
Zhang, Shu
;
Wang, Peng-Ju
;
Zhang, Shuang-Nan
;
Kong, Ling-Da
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/10/23
A 3D-Printed Ferromagnetic Liquid Crystal Elastomer with Programmed Dual-Anisotropy and Multi-Responsiveness
期刊论文
OAI收割
ADVANCED MATERIALS, 2023, 页码: 12
作者:
Sun, Yuxuan
;
Wang, Liu
;
Zhu, Zhengqing
;
Li, Xingxiang
;
Sun, Hong
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2023/10/30
3D printing
anisotropy
ferromagnetic materials
liquid crystal elastomers
programming
Lipids and Terpenoids from the Deep-Sea Fungus
Trichoderma lixii
R22 and Their Antagonism against Two Wheat Pathogens
期刊论文
OAI收割
MOLECULES, 2023, 卷号: 28, 期号: 17, 页码: 10
作者:
Li, Chang-Peng
;
Shi, Zhen-Zhen
;
Fang, Sheng-Tao
;
Song, Yin-Ping
;
Ji, Nai-Yun
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2023/11/15
Trichoderma
lipid
terpenoid
butenolide
brasilane
fungicide