中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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文献情报中心 [44]
植物研究所 [18]
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Discovery of novel triazine derivatives as potent retinoic acid receptor-related orphan receptor gamma t (ROR gamma t) inverse agonists
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 256, 页码: 18
作者:
Lu, Lixue
;
Chen, Song
;
Yu, Mingcheng
;
Zhou, Ronghui
;
Guo, Siqi
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/10/17
ROR gamma t
Triazines
Inverse agonist
Psoriasis
Autoimmune diseases
Selective PPAR gamma modulator diosmin improves insulin sensitivity and promotes browning of white fat
期刊论文
OAI收割
JOURNAL OF BIOLOGICAL CHEMISTRY, 2023, 卷号: 299, 期号: 4, 页码: 14
作者:
Yu, Jian
;
Hu, Yepeng
;
Sheng, Maozheng
;
Gao, Mingyuan
;
Guo, Wenxiu
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2023/10/17
Context-aware network fusing transformer and V-Net for semi-supervised segmentation of 3D left atrium
期刊论文
OAI收割
EXPERT SYSTEMS WITH APPLICATIONS, 2023, 卷号: 214, 页码: 9
作者:
Zhao, Chenji
;
Xiang, Shun
;
Wang, Yuanquan
;
Cai, Zhaoxi
;
Shen, Jun
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2023/07/12
3D MRI
Contextual information
Image segmentation
Semi -supervised learning
Transformers
Design, synthesis of novel benzimidazole derivatives as ENL inhibitors suppressing leukemia cells viability via downregulating the expression of MYC
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 248, 页码: 14
作者:
Guo, Siqi
;
Jia, Tongguan
;
Xu, Xiaoming
;
Yang, Feng
;
Xiao, Senhao
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2023/04/10
ENL Inhibitor
YEATS domain
Histone lysine acetylation
Benzimidazole derivatives
Acute myeloid leukemia
Interannual variation of coastal upwelling around Hainan Island
期刊论文
OAI收割
FRONTIERS IN MARINE SCIENCE, 2023, 卷号: 10, 页码: 10
作者:
Zhu, Junying
;
Zhou, Quanyi
;
Zhou, Qianqing
;
Geng, Xinxing
;
Shi, Jie
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2023/12/13
upwelling
interannual variation
sea surface temperature
wind stress curl
Hainan Island
Design, synthesis, and biological evaluation of novel carbazole derivatives as potent DNMT1 inhibitors with reasonable PK properties
期刊论文
OAI收割
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2022, 卷号: 37, 期号: 1, 页码: 1537-1555
作者:
Li, Ennian
;
Wang, Kai
;
Zhang, Bei
;
Guo, Siqi
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2022/08/16
DNMT1 inhibitor
A549 cell lines
HCT116 cell lines
antitumor activity
pharmacokinetic
An Insight-HXMT View of the mHz Quasi-regular Modulation Phenomenon in the Black Hole X-Ray Binary 4U 1630-47
期刊论文
OAI收割
ASTROPHYSICAL JOURNAL, 2022, 卷号: 937, 期号: 1, 页码: 12
作者:
Yang, Zi-xu
;
Zhang, Liang
;
Huang, Yue
;
Bu, Qingcui
;
Zhang, Zhen
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2023/02/28
A 33-residue peptide tag increases solubility and stability of Escherichia coli produced single-chain antibody fragments
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2022, 卷号: 13, 期号: 1, 页码: 4614
作者:
Wang, Yang
;
Yuan, Wenjie
;
Guo, Siqi
;
Li, Qiqi
;
Chen, Xiaomei
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/03/21
General Pharmacological Activation Mechanism of K+ Channels Bypassing Channel Gates
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 15
作者:
Liu, Shijie
;
Guo, Peipei
;
Wang, Kun
;
Zhang, Shaoying
;
Li, Ya
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2022/08/30
Cytotoxic and Antibacterial Isomalabaricane Terpenoids from the Sponge Rhabdastrella globostellata
期刊论文
OAI收割
JOURNAL OF NATURAL PRODUCTS, 2022, 卷号: 85, 期号: 7, 页码: 1799-1807
作者:
Chen, Bao
;
Qiu, Peiju
;
Xu, Baofu
;
Zhao, Qingmin
;
Gu, Yu-Cheng
  |  
收藏
  |  
浏览/下载:112/0
  |  
提交时间:2024/03/21