机构

• 上海药物研究所 [9]
• 合肥物质科学研究院 [9]
• 过程工程研究所 [2]
• 生态环境研究中心 [2]
• 成都山地灾害与环境研... [1]
• 遥感与数字地球研究所 [1]
• 更多

采集方式

• OAI收割 [27]

内容类型

• 期刊论文 [26]
• 会议论文 [1]

发表日期

• 2024 [1]
• 2023 [6]
• 2022 [1]
• 2020 [2]
• 2019 [1]
• 2018 [1]
• 更多

学科主题

• Environmen... [1]

筛选

浏览/检索结果: 共27条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Structure-based design of potent FABP4 inhibitors with high selectivity against FABP3 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 264, 页码: 10 作者:  Chen, Guofeng;  Xie, Hang;  Liu, Jiayuan;  Shao, Qiang;  Li, Minjun   |  收藏  |  浏览/下载：7/0  |  提交时间：2024/01/26 Methyl substitution  Selectivity  FABP4 inhibitor  Anti-inflammation  Metabolic stability   Drug repurposing and structure-based discovery of new PDE4 and PDE5 inhibitors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 262, 页码: 14 作者:  Liu, Jiayuan;  Zhang, Xianglei;  Chen, Guofeng;  Shao, Qiang;  Zou, Yi   |  收藏  |  浏览/下载：18/0  |  提交时间：2024/01/16 Phosphodiesterase-4 (PDE4)  PDE5  Inhibitor  Drug repurposing  Crystal structure  Structure -guided optimization   Structure-based development and preclinical evaluation of the SARS-CoV-2 3C-like protease inhibitor simnotrelvir 期刊论文  OAI收割 NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 15 作者:  Jiang, Xiangrui;  Su, Haixia;  Shang, Weijuan;  Zhou, Feng;  Zhang, Yan   |  收藏  |  浏览/下载：12/0  |  提交时间：2024/03/25 Ootheca mantidis mitigates renal fibrosis in mice by the suppression of apoptosis via increasing the gut microbe Akkermansia muciniphila and modulating glutamine metabolism 期刊论文  OAI收割 BIOMEDICINE & PHARMACOTHERAPY, 2023, 卷号: 166, 页码: 15 作者:  Wang, Jue;  Guo, Xiaozhen;  Zou, Ziyuan;  Yu, Minjun;  Li, Xueling   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/12/08 Ootheca mantidis  Unilateral ureteral obstruction  Renal interstitial fibrosis  Apoptosis  Akkermansia muciniphila  Glutamine   Structure-Based Design of Potent Peptidomimetic Inhibitors Covalently Targeting SARS-CoV-2 Papain-like Protease 期刊论文  OAI收割 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 10, 页码: 15 作者:  Wang, Qian;  Chen, Guofeng;  He, Jian;  Li, Jiameng;  Xiong, Muya   |  收藏  |  浏览/下载：18/0  |  提交时间：2023/10/17 SARS-CoV-2  papain-like protease  covalent inhibitor  co-crystal structure  in vitro assay   Dipyridamole interacts with the N-terminal domain of HSP90 and antagonizes the function of the chaperone in multiple cancer cell lines 期刊论文  OAI收割 BIOCHEMICAL PHARMACOLOGY, 2023, 卷号: 207, 页码: 16 作者:  Gao, Jing;  Zhou, Chen;  Zhong, Yan;  Shi, Li;  Luo, Xuanyang   |  收藏  |  浏览/下载：16/0  |  提交时间：2023/04/10 HSP90  ATP competitive inhibitors  Tip-based affinity selection-mass spectrometry  Dipyridamole  Cell cycle regulators   High-precision early warning system for rice cadmium accumulation risk assessment 期刊论文  OAI收割 SCIENCE OF THE TOTAL ENVIRONMENT, 2023, 卷号: 859 作者:  Yan, Huili;  Guo, Hanyao;  Li, Ting;  Zhang, Hezifan;  Xu, Wenxiu   |  收藏  |  浏览/下载：2/0  |  提交时间：2024/03/07 Genotype-to-phenotype prediction  Rice  Cd risk early warning   Identification of Cysteine 270 as a Novel Site for Allosteric Modulators of SARS-CoV-2 Papain-Like Protease 期刊论文  OAI收割 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2022, 页码: 10 作者:  Hu, Hangchen;  Wang, Qian;  Su, Haixia;  Shao, Qiang;  Zhao, Wenfeng   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/04/10 Allosteric Modulator  Cysteine 270  Drug Design  Papain-Like Protease  SARS-CoV-2   Exploration of Fragment Binding Poses Leading to Efficient Discovery of Highly Potent and Orally Effective Inhibitors of FABP4 for Anti-inflammation 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 8, 页码: 4090-4106 作者:  Su, Haixia;  Zou, Yi;  Chen, Guofeng;  Dou, Huixia;  Xie, Hang   |  收藏  |  浏览/下载：22/0  |  提交时间：2020/07/01 Mapping essential urban land use categories in China (EULUC-China): preliminary results for 2018 期刊论文  OAI收割 SCIENCE BULLETIN, 2020, 卷号: 65, 期号: 3, 页码: 182-187 作者:  Gong, Peng;  Chen, Bin;  Li, Xuecao;  Liu, Han;  Wang, Jie   |  收藏  |  浏览/下载：193/0  |  提交时间：2020/04/02 Mapping essential  EULUC-China