机构

• 上海药物研究所 [28]

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• OAI收割 [28]

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• Journal A... [28]

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• 2024 [6]
• 2023 [3]
• 2022 [6]
• 2021 [3]
• 2020 [5]
• 2019 [1]
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Browse/Search Results:  1-10 of 28 Help 条数/页： 5101520253035404550556065707580859095100 排序方式： SelectSubmit date AscendingSubmit date DescendingTitle AscendingTitle DescendingIssue Date AscendingIssue Date DescendingAuthor AscendingAuthor Descending Structural basis for recognition of 26RFa by the pyroglutamylated RFamide peptide receptor 期刊论文  OAI收割 CELL DISCOVERY, 2024, 卷号: 10, 期号: 1, 页码: 13 Authors:  Jin, Sanshan;  Guo, Shimeng;  Xu, Youwei;  Li, Xin;  Wu, Canrong   |  Favorite  |  View/Download：9/0  |  Submit date：2024/07/12 A novel approach to exploit Small-Molecule glucagon-like Peptide-1 receptor agonists with high potency 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2024, 卷号: 107, 页码: 19 Authors:  Wang, Xiaoyan;  Yun, Ying;  Chen, Lili;  Guo, Shimeng;  Niu, Buying   |  Favorite  |  View/Download：28/0  |  Submit date：2024/07/12 Diabetes  GLP-1 receptor  Agonist  Structural optimization  Water molecule replacement  Structure activity relationship  Docking simulation   Structural and functional evidence that GPR30 is not a direct estrogen receptor 期刊论文  OAI收割 CELL RESEARCH, 2024, 页码: 4 Authors:  Liu, Heng;  Guo, Shimeng;  Dai, Antao;  Xu, Peiyu;  Li, Xin   |  Favorite  |  View/Download：19/0  |  Submit date：2024/06/27 Cryo-EM structures of adenosine receptor A3AR bound to selective agonists 期刊论文  OAI收割 NATURE COMMUNICATIONS, 2024, 卷号: 15, 期号: 1, 页码: 10 Authors:  Cai, Hongmin;  Guo, Shimeng;  Xu, Youwei;  Sun, Jun;  Li, Junrui   |  Favorite  |  View/Download：32/0  |  Submit date：2024/06/27 Discovery of betulinic acid derivatives as gut-restricted TGR5 agonists: Balancing the potency and physicochemical properties 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2024, 卷号: 144, 页码: 18 Authors:  Zhuo, Ning;  Yun, Ying;  Zhang, Chenlu;  Guo, Shimeng;  Yin, Jianpeng   |  Favorite  |  View/Download：28/0  |  Submit date：2024/03/25 Type 2 Diabetes  TGR5 agonist  Betulinic acid  Gut-restricted  Gallbladder-filling effects  Kinetophores   Discovery and exploration of novel somatostatin receptor subtype 5 (SSTR5) antagonists for the treatment of cholesterol gallstones 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 264, 页码: 16 Authors:  Han, Fanghui;  Zhao, Tingting;  Zhang, Yanglong;  Yun, Ying;  Xu, Yuanyuan   |  Favorite  |  View/Download：12/0  |  Submit date：2024/02/19 SSTR5 antagonist  Gallbladder emptying  Cholesterol gallstones   Discovery of a novel GPR35 agonist with high and equipotent species potency for oral treatment of IBD 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 96, 页码: 12 Authors:  Song, Zhaoxiang;  Lu, Dan;  Sun, Jun;  Ye, Yangliang;  Fang, Jiahui   |  Favorite  |  View/Download：42/0  |  Submit date：2024/01/16 GPR35  IBD  Lodoxamide   Design and Synthesis Studies of α-Methylene-γ-butyrolactones Antagonists of GPR52 期刊论文  OAI收割 CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2023, 卷号: 43, 期号: 11, 页码: 3916-3929 Authors:  Shen, Donghang;  Li, Xin;  Guo, Shimeng;  Xie, Xin;  Nan, Fajun   |  Favorite  |  View/Download：25/0  |  Submit date：2024/02/27 Huntingdon's disease  G protein-coupled receptor  GPR52  alpha-methylene-gamma-butyrolactones  antagonist   Discovery of Novel 5,6-Dihydro-1,2,4-triazine Derivatives as Efficacious Glucagon-Like Peptide-1 Receptor Agonists 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 23 Authors:  Chen, Lili;  Yun, Ying;  Guo, Shimeng;  Wang, Xiaoyan;  Xiong, Muya   |  Favorite  |  View/Download：14/0  |  Submit date：2023/10/17 Structures of adenosine receptor A(2B)R bound to endogenous and synthetic agonists 期刊论文  OAI收割 CELL DISCOVERY, 2022, 卷号: 8, 期号: 1, 页码: 4 Authors:  Cai, Hongmin;  Xu, Youwei;  Guo, Shimeng;  He, Xinheng;  Sun, Jun   |  Favorite  |  View/Download：20/0  |  Submit date：2023/04/10