中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共22条,第1-10条 帮助

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A task-specific encoding algorithm for RNAs and RNA-associated interactions based on convolutional autoencoder 期刊论文  OAI收割
NUCLEIC ACIDS RESEARCH, 2023, 页码: 14
作者:  
Wang, Yunxia;  Pan, Ziqi;  Mou, Minjie;  Xia, Weiqi;  Zhang, Hongning
  |  收藏  |  浏览/下载:6/0  |  提交时间:2023/12/08
Novel thieno[2,3-b]quinoline-procaine hybrid molecules: A new class of allosteric SHP-1 activators evolved from PTP1B inhibitors 期刊论文  OAI收割
CHINESE CHEMICAL LETTERS, 2023, 卷号: 34, 期号: 8, 页码: 6
作者:  
Xu, Lei;  Xuyan, Xuyang;  Minmi, Minmin;  Wang, Zhiji;  Shee, Chao
  |  收藏  |  浏览/下载:26/0  |  提交时间:2023/10/17
RNAincoder: a deep learning-based encoder for RNA and RNA-associated interaction 期刊论文  OAI收割
NUCLEIC ACIDS RESEARCH, 2023, 页码: 11
作者:  
Wang, Yunxia;  Chen, Zhen;  Pan, Ziqi;  Huang, Shijie;  Liu, Jin
  |  收藏  |  浏览/下载:18/0  |  提交时间:2023/10/17
Learning with uncertainty to accelerate the discovery of histone lysine-specific demethylase 1A (KDM1A/LSD1) inhibitors 期刊论文  OAI收割
BRIEFINGS IN BIOINFORMATICS, 2022, 页码: 14
作者:  
Wang, Dong;  Wu, Zhenxing;  Shen, Chao;  Bao, Lingjie;  Luo, Hao
  |  收藏  |  浏览/下载:25/0  |  提交时间:2023/04/10
Discovery of a Novel Androgen Receptor Antagonist Manifesting Evidence to Disrupt the Dimerization of the Ligand-Binding Domain via Attenuating the Hydrogen-Bonding Network Between the Two Monomers 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64
作者:  
Fu, Weitao;  Zhang, Minkui;  Liao, Jianing;  Tang, Qing;  Lei, Yixuan
  |  收藏  |  浏览/下载:30/0  |  提交时间:2022/03/21
Structural insights into ligand recognition and activation of the melanocortin-4 receptor 期刊论文  OAI收割
CELL RESEARCH, 2021, 页码: 13
作者:  
Zhang, Huibing;  Chen, Li-Nan;  Yang, Dehua;  Mao, Chunyou;  Shen, Qingya
  |  收藏  |  浏览/下载:65/0  |  提交时间:2021/11/04
Development of MIF/IL-1β biosensors for discovery of critical quality attributes and potential allergic rhinitis targets from clinical real-world data by intelligent algorithm coupled with in vitro an 期刊论文  OAI收割
BIOSENSORS & BIOELECTRONICS, 2021, 卷号: 194, 页码: 113608
作者:  
Ma, Lijuan;   Zheng, Yanfei;   Wang, Ji;   Li, Qianqian;   Zeng, Jingqi;   Wang, Zijian;   Hou, Tingjun;   Zhang, Yang;   Li, Mingshuang;   Shen, Rongmin;   Chen, Xuemei;   Qin, Jingbo;   Lei, Leting;   Xia, Qing;   Wang, Qi;   Qiao, Yanjiang;   Wu, Zhisheng
  |  收藏  |  浏览/下载:19/0  |  提交时间:2022/03/23
Discovery of Novel Androgen Receptor Ligands by Structure-based Virtual Screening and Bioassays 期刊论文  OAI收割
GENOMICS PROTEOMICS & BIOINFORMATICS, 2019, 卷号: 16, 期号: 6, 页码: 416-427
作者:  
Hou, Tingjun;  Li, Dan;  Chang, Shan;  Xu, Lei;  Sun, Huiyong
  |  收藏  |  浏览/下载:260/0  |  提交时间:2019/06/24
Major advances in studies of the physical geography and living environment of China during the past 70 years and future prospects 期刊论文  OAI收割
SCIENCE CHINA-EARTH SCIENCES, 2019, 卷号: 62, 期号: 11, 页码: 1665-1701
作者:  
Chen, Fahu;  Fu, Bojie;  Xia, Jun;  Wu, Duo;  Wu, Shaohong
  |  收藏  |  浏览/下载:50/0  |  提交时间:2020/06/03
Major advances in studies of the physical geography and living environment of China during the past 70 years and future prospects 期刊论文  OAI收割
SCIENCE CHINA-EARTH SCIENCES, 2019, 卷号: 62, 期号: 11, 页码: 1665-1701
作者:  
Chen, Fahu;  Fu, Bojie;  Xia, Jun;  Wu, Duo;  Wu, Shaohong
  |  收藏  |  浏览/下载:90/0  |  提交时间:2020/05/19