中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共8条,第1-8条 帮助

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Discovery of novel 3-hydroxypicolinamides as selective inhibitors of HIV-1 integrase-LEDGF/p75 interaction 期刊论文  OAI收割
European Journal of Medicinal Chemistry, 2017, 卷号: 125, 期号: X, 页码: 1051-1063
作者:  
Zhang FH;  Debnath B;  Zheng YT;  Neamati N[*];  Long YQ[*]
收藏  |  浏览/下载:72/0  |  提交时间:2016/11/07
Design and discovery of flavonoid-based HIV-1 integrase inhibitors targeting both the active site and the interaction with LEDGF/p75 期刊论文  OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2014, 卷号: 22, 期号: 12, 页码: 3146-3158
作者:  
Li BW;  Zhang FH;  Serrao E;  Chen H;  Sanchez TW
收藏  |  浏览/下载:10/0  |  提交时间:2014/10/15
Repositioning HIV‑1 Integrase Inhibitors for Cancer Therapeutics: 1,6-Naphthyridine-7-carboxamide as a Promising Scaffold with Drug-like Properties 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2012, 卷号: 55, 期号: 22, 页码: 9492-9509
作者:  
Zeng LF;  Wang Y;  Kazemi R;  Xu SL;  Xu ZL
收藏  |  浏览/下载:13/0  |  提交时间:2013/04/09
Efficient synthesis and utilization of phenyl-substituted heteroaromatic carboxylic acids as aryl diketo acid isosteres in the design of novel HIV-1 integrase inhibitors 期刊论文  OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2008, 卷号: 18, 期号: 16, 页码: 4521-4524
作者:  
Zeng LF;  Zhang HS;  Wang YH;  Sanchez T;  Zheng YT
收藏  |  浏览/下载:14/0  |  提交时间:2010/08/24
Rational design and synthesis of novel dimeric diketoacid-containing inhibitors of HIV-1 integrase: Implication for binding to two metal ions on the active site of integrase 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2004, 卷号: 47, 期号: 10, 页码: 2561-2573
作者:  
Long, YQ;  Jiang, XH;  Dayam, R;  Sanchez, T;  Shoemaker, R
  |  收藏  |  浏览/下载:10/0  |  提交时间:2019/01/08