中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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A new method for spatial three-dimensional prediction of soil heavy metals contamination
期刊论文
OAI收割
CATENA, 2024, 卷号: 235, 页码: 12
作者:
Shen, Fengbei
;
Xu, Chengdong
;
Wang, Jinfeng
;
Hu, Maogui
;
Guo, Guanlin
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/01/02
Spatial pattern
Spatial stratified heterogeneity
Geodetector
Statistical model
Estimation uncertainty
Polycyclic aromatic hydrocarbons (PAHs) evidence for frequent combustion events on land during the Permian–Triassic transition in Northwest China
期刊论文
OAI收割
Palaeogeography, Palaeoclimatology, Palaeoecology, 2024, 卷号: 642, 页码: 112152
作者:
Jiao, Sheng-lin
;
Zhang, Hua(张华)
;
Cai, Yao-feng
;
Jin, Chuan-fang
;
Shen, Shu-zhong
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/04/15
Distinctive roles of L-type calcium channels subtypes within the dorsal hippocampus in formation of morphine withdrawal-induced aversion in rats
期刊论文
OAI收割
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, 2023, 卷号: 127, 页码: 8
作者:
Duan, Ying
;
Jin, Lingtong
;
Du, Wenjie
;
Meng, Yiming
;
Liang, Jing
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/10/09
Opiate withdrawal
conditioned place aversion (CPA)
dorsal hippocampus (DH)
LTCCs subtypes
RNA interference
Discovery of a novel GPR35 agonist with high and equipotent species potency for oral treatment of IBD
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 96, 页码: 12
作者:
Song, Zhaoxiang
;
Lu, Dan
;
Sun, Jun
;
Ye, Yangliang
;
Fang, Jiahui
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2024/01/16
GPR35
IBD
Lodoxamide
A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects
期刊论文
OAI收割
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 卷号: 191, 页码: 9
作者:
Yang, Xin-Mei
;
Yang, Yang
;
Yao, Bu-Fan
;
Ye, Pan-Pan
;
Xu, Yan
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/12/11
COVID-19
Simnotrelvir
Safety
Pharmacokinetics
Healthy subjects
Preclinical and early clinical studies of a novel compound SYHA1813 that efficiently crosses the blood-brain barrier and exhibits potent activity against glioblastoma
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4748-4764
作者:
Liu, Yingqiang
;
Zhan, Zhengsheng
;
Kang, Zhuang
;
Li, Mengyuan
;
Lv, Yongcong
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/01/26
Small molecule inhibitor
Tumor microenvironment
Immune-checkpoint
immune-deficient mouse models
including temozolomide (TMZ) insensitive tumors. Notably
Oral pectin/oligochitosan microspheres for colon-specific controlled release of quercetin to treat inflammatory bowel disease
期刊论文
OAI收割
CARBOHYDRATE POLYMERS, 2023, 卷号: 316, 页码: 15
作者:
Jing, Shisuo
;
Chen, Huayuan
;
Liu, Ergang
;
Zhang, Meng
;
Shen, Huan
  |  
收藏
  |  
浏览/下载:88/0
  |  
提交时间:2023/10/17
Inflammatory bowel disease
Quercetin
colon-targeted delivery
Pectin microsphere
Oligochitosan
Immune microenvironment
3D printing in materials manufacturing industry: A realm of Industry 4.0
期刊论文
OAI收割
HELIYON, 2023, 卷号: 9, 期号: 9, 页码: 20
作者:
Tamir, Tariku Sinshaw
;
Xiong, Gang
;
Shen, Zhen
;
Leng, Jiewu
;
Fang, Qihang
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/02/21
3D printing
Additive manufacturing
Closed-loop control
Machine learning
Industry 4.0
Preclinical Evaluation of 9MW2821, a Site-Specific Monomethyl Auristatin E-based Antibody-Drug Conjugate for Treatment of Nectin-4-expressing Cancers
期刊论文
OAI收割
MOLECULAR CANCER THERAPEUTICS, 2023, 卷号: 22, 期号: 8, 页码: 913-925
作者:
Zhou, Wei
;
Fang, Peng
;
Yu, Dongan
;
Ren, Hongyuan
;
You, Meng
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/10/17
TGR5 agonist inhibits intestinal epithelial cell apoptosis via cAMP/PKA/c-FLIP/JNK signaling pathway and ameliorates dextran sulfate sodium-induced ulcerative colitis
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 卷号: 44, 期号: 8, 页码: 1649-1664
作者:
Yang, Wen-ji
;
Han, Fang-hui
;
Gu, Yi-pei
;
Qu, Hui
;
Liu, Jia
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/03/27
TGR5 agonist
ulcerative colitis
intestinal epithelial cell
apoptosis
cAMP
PKA signaling pathway
c-FLIP