中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [21]
海洋研究所 [6]
化学研究所 [5]
广州能源研究所 [5]
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武汉病毒研究所 [2]
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期刊论文 [49]
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2024 [1]
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A novel pterostilbene compound DCZ0825 induces macrophage M1 differentiation and Th1 polarization to exert anti-myeloma and immunomodulatory
期刊论文
OAI收割
INTERNATIONAL IMMUNOPHARMACOLOGY, 2024, 卷号: 127, 页码: 14
作者:
Zhang, Hui
;
Hu, Ke
;
Lu, Yumeng
;
Xu, Zhijian
;
Chen, Gege
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/03/25
Multiple myeloma
M1 macrophages
Th1 cells
Immunomodulatory
Berberine derivative DCZ0358 induce oxidative damage by ROS-mediated JNK signaling in DLBCL cells
期刊论文
OAI收割
INTERNATIONAL IMMUNOPHARMACOLOGY, 2023, 卷号: 125, 页码: 15
作者:
Feng, Qilin
;
Hu, Ke
;
Hu, Huifang
;
Lu, Yumeng
;
Zhang, Hui
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2024/01/16
DLBCL
ROS
DNA damage
JNK
Mitochondrial dysfunction
Dihydrocelastrol induces antitumor activity and enhances the sensitivity of bortezomib in resistant multiple myeloma by inhibiting STAT3-dependent PSMB5 regulation
期刊论文
OAI收割
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2023, 卷号: 55, 期号: 12, 页码: 1884-1891
作者:
Jin, Shuhan
;
Li, Bo
;
Zhang, Bibo
;
Gao, Xuejie
;
Jia, Xinyan
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/02/27
dihydrocelastrol
multiple myeloma
JAK2/STAT3
PSMB5
bortezomib resistance
The novel norcantharidin derivative DCZ5417 suppresses multiple myeloma progression by targeting the TRIP13-MAPK-YWHAE signaling pathway
期刊论文
OAI收割
JOURNAL OF TRANSLATIONAL MEDICINE, 2023, 卷号: 21, 期号: 1, 页码: 17
作者:
Wang, Yingcong
;
Dong, Sanfeng
;
Hu, Ke
;
Xu, Li
;
Feng, Qilin
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/01/26
Norcantharidin
Derivative
DCZ5417
TRIP13
Anti-myeloma
MAPK
TI17, a novel compound, exerts anti-MM activity by impairing Trip13 function of DSBs repair and enhancing DNA damage
期刊论文
OAI收割
CANCER MEDICINE, 2023, 页码: 14
作者:
Chang, Shuaikang
;
Xiao, Wenqin
;
Xie, Yongsheng
;
Xu, Zhijian
;
Li, Bo
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2023/12/11
DNA damage
DSBs repair
myeloma
TI17
Trip13
Molecular mechanism by which RRM2-inhibitor (cholagogue osalmid) plus bafilomycin A1 cause autophagic cell death in multiple myeloma
期刊论文
OAI收割
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2023, 卷号: 747, 页码: 12
作者:
Guo, Shushan
;
Xu, Zhijian
;
Feng, Qilin
;
Zhang, Hui
;
Yu, Dandan
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/12/11
Autophagy
RRM2
p62
RIPK3
Cholagogue osalmid
Bafilomycin A1
Aberrant activation of TRIP13-EZH2 signaling axis promotes stemness and therapy resistance in multiple myeloma
期刊论文
OAI收割
LEUKEMIA, 2023, 页码: 4
作者:
Xu, Li
;
Wang, Yingcong
;
Wang, Guanli
;
Guo, Shushan
;
Yu, Dandan
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2023/10/17
A novel alkaloid compound, DCZ0358, exerts significant antitumor activity in bortezomib-resistant multiple myeloma cells through inhibition of JAK2/STAT3 pathway
期刊论文
OAI收割
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2023, 卷号: 55, 期号: 2, 页码: 215
作者:
Zhang Bibo
;
Li Bo
;
Xie Yongsheng
;
Chang Shuaikang
;
Xu Zhijian
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/07/18
DCZ0358
apoptosis
cell cycle arrest
multiple myeloma
JAK2/STAT3 pathway
Potentiation of Vancomycin: Creating Cooperative Membrane Lysis through a "Derivatization-for-Sensitization" Approach
期刊论文
OAI收割
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2022, 卷号: 144, 期号: 23, 页码: 10622-10639
作者:
Lei, E.
;
Tao, Huanyu
;
Jiao, Shang
;
Yang, Anming
;
Zhou, Yu
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2022/08/16
Preclinical validation and phase I trial of 4-hydroxysalicylanilide, targeting ribonucleotide reductase mediated dNTP synthesis in multiple myeloma
期刊论文
OAI收割
Journal of Biomedical Science, 2022, 卷号: 29, 期号: 1
作者:
Xie,Yongsheng
;
Wang,Yingcong
;
Xu,Zhijian
;
Lu,Yumeng
;
Song,Dongliang
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2022/06/15
4-Hydroxysalicylanilid
Ribonucleotide reductase
Deoxyribonucleotides
DNA damage repair
Multiple myeloma