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Chinese Academy of Sciences Institutional Repositories Grid
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A novel pterostilbene compound DCZ0825 induces macrophage M1 differentiation and Th1 polarization to exert anti-myeloma and immunomodulatory
期刊论文
OAI收割
INTERNATIONAL IMMUNOPHARMACOLOGY, 2024, 卷号: 127, 页码: 14
作者:
Zhang, Hui
;
Hu, Ke
;
Lu, Yumeng
;
Xu, Zhijian
;
Chen, Gege
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/03/25
Multiple myeloma
M1 macrophages
Th1 cells
Immunomodulatory
Discovery and optimization of thieno[3,2-d]pyrimidine derivatives as highly selective inhibitors of cyclin-dependent kinase 7
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 263, 页码: 21
作者:
Zhang, Hongjin
;
Lin, Guohao
;
Jia, Suyun
;
Zhang, Ying
;
Wu, Jianbo
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/01/26
Thieno[3
d ]pyrimidine derivative
Cyclin-dependent kinase 7
Small molecule inhibitor
Kinome selectivity
Triple negative breast cancer
Effect of topographic slope on the interaction between debris flows and riparian forests
期刊论文
OAI收割
LANDSLIDES, 2023, 页码: 12
作者:
Cui, Wen-rong
;
Chen, Jian-gang
;
Chen, Xiao-qing
;
Song, Dong-ri
;
Zhao, Wan-yu
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/03/14
Riparian forests
Debris flows
Slope
Ecological measures
A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects
期刊论文
OAI收割
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 卷号: 191, 页码: 9
作者:
Yang, Xin-Mei
;
Yang, Yang
;
Yao, Bu-Fan
;
Ye, Pan-Pan
;
Xu, Yan
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/12/11
COVID-19
Simnotrelvir
Safety
Pharmacokinetics
Healthy subjects
Berberine derivative DCZ0358 induce oxidative damage by ROS-mediated JNK signaling in DLBCL cells
期刊论文
OAI收割
INTERNATIONAL IMMUNOPHARMACOLOGY, 2023, 卷号: 125, 页码: 15
作者:
Feng, Qilin
;
Hu, Ke
;
Hu, Huifang
;
Lu, Yumeng
;
Zhang, Hui
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2024/01/16
DLBCL
ROS
DNA damage
JNK
Mitochondrial dysfunction
Dihydrocelastrol induces antitumor activity and enhances the sensitivity of bortezomib in resistant multiple myeloma by inhibiting STAT3-dependent PSMB5 regulation
期刊论文
OAI收割
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2023, 卷号: 55, 期号: 12, 页码: 1884-1891
作者:
Jin, Shuhan
;
Li, Bo
;
Zhang, Bibo
;
Gao, Xuejie
;
Jia, Xinyan
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/02/27
dihydrocelastrol
multiple myeloma
JAK2/STAT3
PSMB5
bortezomib resistance
Revisiting the Seasonal Evolution of the Indian Ocean Dipole from the Perspective of Process-Based Decomposition
期刊论文
OAI收割
JOURNAL OF OCEAN UNIVERSITY OF CHINA, 2023, 卷号: 22, 期号: 6, 页码: 1453-1463
作者:
Zhang, Guangli
;
Fan, Hanjie
;
Huang, Ke
;
Long, Tong
;
Song, Wei
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/02/26
Indian Ocean Dipole
climate feedback-response analysis method
growth rate of the sea surface temperature anomaly
seasonally dependent sea surface temperature anomaly
water vapor feedback
The novel norcantharidin derivative DCZ5417 suppresses multiple myeloma progression by targeting the TRIP13-MAPK-YWHAE signaling pathway
期刊论文
OAI收割
JOURNAL OF TRANSLATIONAL MEDICINE, 2023, 卷号: 21, 期号: 1, 页码: 17
作者:
Wang, Yingcong
;
Dong, Sanfeng
;
Hu, Ke
;
Xu, Li
;
Feng, Qilin
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/01/26
Norcantharidin
Derivative
DCZ5417
TRIP13
Anti-myeloma
MAPK
TI17, a novel compound, exerts anti-MM activity by impairing Trip13 function of DSBs repair and enhancing DNA damage
期刊论文
OAI收割
CANCER MEDICINE, 2023, 页码: 14
作者:
Chang, Shuaikang
;
Xiao, Wenqin
;
Xie, Yongsheng
;
Xu, Zhijian
;
Li, Bo
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2023/12/11
DNA damage
DSBs repair
myeloma
TI17
Trip13
Pointing calibration of LHAASO-WFCTA telescopes using bright stars
期刊论文
OAI收割
Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 2023, 卷号: 1056
作者:
Cao, Zhen
;
Aharonian, F.
;
An, Q.
;
Axikegu
;
Bai, Y. X.
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2023/10/07