中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [15]
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期刊论文 [47]
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Structure-based identification of new orally bioavailable BRD9-PROTACs for treating acute myelocytic leukemia
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 262, 页码: 18
作者:
Zhang, Jingyu
;
Duan, Haiting
;
Gui, Renzhao
;
Wu, Mingfei
;
Shen, Liteng
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/12/19
Acute myeloid leukemia
Bromodomain-containing protein 9
Proteolysis-targeting chimera
Orally bioavailable
Docking
A one-component phosphonium borane Lewis pair serves as a dual initiator and catalyst in the ring-opening alternating copolymerization of anhydrides and epoxides
期刊论文
OAI收割
POLYMER CHEMISTRY, 2022, 卷号: 13, 期号: 47, 页码: 6551-6563
作者:
Hui, Jiwen
;
Wang, Xiaowu
;
Yao, Xiaoqian
;
Li, Zhibo
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2023/02/24
Structure-based rational design enables efficient discovery of a new selective and potent AKT PROTAC degrader
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 238, 页码: 15
作者:
Zhu, Cheng-Liang
;
Luo, Xiaomin
;
Tian, Tian
;
Rao, Zijian
;
Wang, Hanlin
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2022/08/16
AKT
Protein kinase B
PROTAC
Chemical degrader
Rational design
Improving the high-cycle fatigue life of a high-strength spring steel for automobiles by suitable shot peening and heat treatment
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF FATIGUE, 2022, 卷号: 161, 页码: 13
作者:
Xia, Bo
;
Wang, Bin
;
Zhang, Peng
;
Ren, Chuanxi
;
Duan, Qiqiang
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2022/07/14
Spring steel
Shot peening intensity
Heat treatment
High-cycle fatigue life
Microstructure
Structural Feature Analyzation Strategies toward Discovery of Orally Bioavailable PROTACs of Bruton's Tyrosine Kinase for the Treatment of Lymphoma
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 13, 页码: 9096–9125
作者:
Zhang, Jingyu
;
Che, Jinxin
;
Luo, Xiaomin
;
Wu, Mingfei
;
Kan, Weijuan
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/03/21
Microstructural and mechanical evolution of SiCf/SiC composites in wet oxygen atmosphere above 1000 degrees C
期刊论文
OAI收割
CERAMICS INTERNATIONAL, 2022, 卷号: 48, 期号: 6, 页码: 8473-8480
作者:
Guo, Feiyu
;
Chen, Xiaowu
;
Cheng, Guofeng
;
Wu, Huiyang
;
Zhou, Haijun
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2022/06/15
Wet-oxygen
SiCf/SiC
Residual stress
Bending strength
Raman spectra
Identification of 2-Aminopyrimidine Derivatives as FLT3 Kinase Inhibitors with High Selectivity over c-KIT
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 4, 页码: 3229-3248
作者:
Tong, Lexian
;
Wang, Peipei
;
Li, Xuemei
;
Dong, Xiaowu
;
Hu, Xiaobei
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2022/08/16
Ecological Drivers of the Soil Microbial Diversity and Composition in Primary Old-Growth Forest and Secondary Woodland in a Subtropical Evergreen Broad-Leaved Forest Biome in the Ailao Mountains, China
期刊论文
OAI收割
FRONTIERS IN MICROBIOLOGY, 2022, 卷号: 13, 页码: 908257
作者:
Zeng, Qingchao
;
Lebreton, Annie
;
Man, Xiaowu
;
Jia, Liukun
;
Wang, Gengshen
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2024/03/11
Advancing COVID-19 diagnosis with privacy-preserving collaboration in artificial intelligence
期刊论文
OAI收割
NATURE MACHINE INTELLIGENCE, 2021, 卷号: 3, 期号: 12, 页码: 1081-1089
作者:
Bai, Xiangd
;
Wang, Hanchen
;
Ma, Liya
;
Xu, Yongchao
;
Gan, Jiefeng
  |  
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2022/01/18
Effect of Defects on High Cycle Fatigue Property of Selective Laser Melted Ti6Al4V Alloy
期刊论文
OAI收割
RARE METAL MATERIALS AND ENGINEERING, 2021, 卷号: 50, 期号: 12, 页码: 4429-4436
作者:
Liu Lun
;
Zhang Zhenjun
;
Yang Huajie
;
Ji Haibin
;
Chen Jie
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2022/07/01
selective laser melting
Ti6Al4V alloy
microstructure
defect
high cycle fatigue property