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Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [20]
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Reversal of subtype-selectivity and function by the introduction of a para-benzamidyl substituent to N-cyclopropylmethyl nornepenthone
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 258, 页码: 15
作者:
Kong, Linghui
;
Ning, Kuan
;
Liu, Xiao
;
Lu, Jiashuo
;
Chen, Baiyu
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2023/10/17
N-cyclopropylmethyl nornepenthone derivatives
derivatives
Structure-activity relationship
MOR antagonist
Functional reversal
Reversal of subtype-selectivity
Opioid use disorder
Discovery of novel triazine derivatives as potent retinoic acid receptor-related orphan receptor gamma t (ROR gamma t) inverse agonists
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 256, 页码: 18
作者:
Lu, Lixue
;
Chen, Song
;
Yu, Mingcheng
;
Zhou, Ronghui
;
Guo, Siqi
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2023/10/17
ROR gamma t
Triazines
Inverse agonist
Psoriasis
Autoimmune diseases
Optimization of carbazole carboxamide RORγt agonists: Challenges in improving the metabolic stability and maintaining the agonistic activity
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 251, 页码: 115213
作者:
Sun, Nannan
;
Yu, Mingcheng
;
Jiang, Zhengyuan
;
Yang, Feng
;
Lu, Lixue
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/03/27
ROR?t agonists
Carbazole carboxamide
Agonistic activity
Metabolic stability
Co-crystallization
Molecular docking
Molecular Mechanisms of Mercury-Sensitive Aquaporins
期刊论文
OAI收割
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2022, 页码: 13
作者:
Xie, Huayong
;
Ma, Shaojie
;
Zhao, Yongxiang
;
Zhou, Hu
;
Tong, Qiong
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2023/04/10
Dynamic Interactions Between Brilliant Green and MscL Investigated by Solid-State NMR Spectroscopy and Molecular Dynamics Simulations
期刊论文
OAI收割
CHEMISTRY-A EUROPEAN JOURNAL, 2022, 页码: 12
作者:
Ma, Shaojie
;
Zhang, Yan
;
Zhang, Xuning
;
Xie, Huayong
;
Tong, Qiong
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2023/04/10
Antibiotic
Brilliant Green
mechanosensitive channel of large conductance (MscL)
molecule dynamics simulations
solid-state NMR
Impact of individualized pharmaceutical care on efficacy and safety of opioid-tolerant outpatients with cancer pain: a multicenter randomized controlled trial
期刊论文
OAI收割
ANNALS OF TRANSLATIONAL MEDICINE, 2022
作者:
Ding, Haiying
;
Song, Yu
;
Wu, Nan
;
Zheng, Xiaowei
;
Wei, Qing
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2022/12/22
Cancer pain
pharmacists
pharmaceutical service
opioids
outpatients
Optimization and Experimental Study of Bionic Compliant End-effector for Robotic Cherry Tomato Harvesting
期刊论文
OAI收割
JOURNAL OF BIONIC ENGINEERING, 2022, 卷号: 19
作者:
Xie, Huaibei
;
Kong, Deyi
;
Wang, Qiong
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2022/12/23
Compliant end-effector
Bio-inspired tarsus gripper
Response surface
Configuration optimization
Cherry tomato
Robotic harvesting
SLL-627 Is a Highly Selective and Potent ? Opioid Receptor (KOR) Agonist with an Unexpected Nonreduction in Locomotor Activity
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 16
作者:
Kong, Linghui
;
Shu, Xuelian
;
Tang, Siyuan
;
Ye, Rongrong
;
Sun, Huijiao
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2022/08/30
Electromagnetic and mechanical properties of CORC cable due to screening current
期刊论文
OAI收割
Superconductor Science and Technology, 2022, 卷号: 35
作者:
Wu,Qiong
;
Wang,Yifan
;
Huang,Ziyi
;
Xie,Yiming
;
He,Rui
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2022/12/22
CORC cable
screening current
electromagnetic property
mechanical property
Applicability of Grassland Production Estimation Using Remote Sensing for the Mongolian Plateau by Comparing Typical Regions in China and Mongolia
期刊论文
OAI收割
SUSTAINABILITY, 2022, 卷号: 14, 期号: 5, 页码: 16
作者:
Li, Qiong
;
Wang, Juanle
;
Xie, Hongquan
;
Ochir, Altansukh
;
Davaasuren, Davaadorj
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2022/09/21
grassland production
interpolation method
remote sensing monitoring
sparse sample points
Mongolian Plateau