中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [150]
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Discovery of betulinic acid derivatives as gut-restricted TGR5 agonists: Balancing the potency and physicochemical properties
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 144, 页码: 18
作者:
Zhuo, Ning
;
Yun, Ying
;
Zhang, Chenlu
;
Guo, Shimeng
;
Yin, Jianpeng
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/03/25
Type 2 Diabetes
TGR5 agonist
Betulinic acid
Gut-restricted
Gallbladder-filling effects
Kinetophores
Eleven highly oxygenated and anti-inflammatory guaian-8,12-olides from Hedyosmum orientale
期刊论文
OAI收割
TETRAHEDRON, 2024, 卷号: 152, 页码: 8
作者:
Fan, Yao-Yue
;
Zhang, Xin-Ru
;
Zheng, Cheng-Yu
;
Li, Ying
;
Yue, Jian-Min
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/03/25
Hedyosmum orientale
Natural products
Guaian-8,12-olide
Structure elucidation
Anti-inflammatory activity
Koilodenoids A-G, immunosuppressive spiro dimers of diterpenoids from
Koilodepas hainanense
: structural elucidation and biomimetic transformation
期刊论文
OAI收割
ORGANIC CHEMISTRY FRONTIERS, 2024, 页码: 8
作者:
Ren, Yu
;
Zheng, Cheng-Yu
;
Yao, Jia-Ying
;
He, Shi-Jun
;
Fan, Yao-Yue
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/03/06
Ecosystem responses dominate the trends of annual gross primary productivity over terrestrial ecosystems of China during 2000-2020
期刊论文
OAI收割
AGRICULTURAL AND FOREST METEOROLOGY, 2023, 卷号: 343, 页码: 109758
作者:
Zhu, Xian-Jin
;
Yu, Gui-Rui
;
Chen, Zhi
;
Zhang, Wei-Kang
;
Han, Lang
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/12/04
Carbon cycles
Eddy covariance
Terrestrial ecosystems
Machine learning
Ecosystem responses
Multi-harmonic structured illumination-based optical diffraction tomography
期刊论文
OAI收割
Applied Optics, 2023, 卷号: 62, 期号: 35, 页码: 9199-9206
作者:
Liu, Ruihua
;
Wen, Kai
;
Li, Jiaoyue
;
Ma, Ying
;
Zheng, Juanjuan
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/01/12
Tetrandrine synergizes with MAPK inhibitors in treating KRAS-mutant pancreatic ductal adenocarcinoma via collaboratively modulating the TRAIL-death receptor axis
期刊论文
OAI收割
PHARMACOLOGICAL RESEARCH, 2023, 卷号: 197, 页码: 12
作者:
Tang, Shuai
;
Duan, Yichen
;
Yuan, Tao
;
Hu, Yutinh
;
Yuan, Liang
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2023/12/11
KRAS
Pancreatic ductal adenocarcinoma
MAPK pathway
Tetrandrine
TRAIL
Death receptors
Anxiolytic effect of antidiabetic metformin is mediated by AMPK activation in mPFC inhibitory neurons
期刊论文
OAI收割
MOLECULAR PSYCHIATRY, 2023, 页码: 11
作者:
Zhang, Yong-mei
;
Zong, Hai-chao
;
Qi, Ying-bei
;
Chang, Liu-liu
;
Gao, Ya-nan
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2023/12/08
Prelimbic cortex dynorphin/& kappa; opioid receptor system modulates methamphetamine-induced cognitive impairment
期刊论文
OAI收割
ADDICTION BIOLOGY, 2023, 卷号: 28, 期号: 9, 页码: 12
作者:
Cheng, Ying-jie
;
Deng, Ying-zhi
;
Deng, Di
;
Wu, Man-qing
;
Chai, Jing-rui
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2023/10/17
cognitive impairment
dynorphin
methamphetamine
prelimbic cortex
& kappa
opioid receptor
DZ2002 alleviates corneal angiogenesis and inflammation in rodent models of dry eye disease via regulating STAT3-PI3KAkt-NF-kappa B pathway
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 14
作者:
Wu, Chun-mei
;
Mao, Jia-wen
;
Zhu, Jin-zhi
;
Xie, Can-can
;
Yao, Jia-ying
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/10/17
dry eye disease
DZ2002
corneal angiogenesis
immunomodulatory function
NF-kappa B
ophthalmic therapy
Identification of XAF1 as an endogenous AKT inhibitor
期刊论文
OAI收割
CELL REPORTS, 2023, 卷号: 42, 期号: 7, 页码: 25
作者:
Chen, Min
;
Wang, Kangjunjie
;
Han, Ying
;
Yan, Shukun
;
Yuan, Huairui
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/10/17