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浏览/检索结果: 共202条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Discovery of a 1,6-naphthyridin-4-one-based AXL inhibitor with improved pharmacokinetics and enhanced in vivo antitumor efficacy 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 17 作者:  Lan, Yaohan;  Peng, Xia;  Ji, Yinchun;  Su, Yi;  Duan, Wenhu   |  收藏  |  浏览/下载：7/0  |  提交时间：2024/02/27 AXL inhibitor  In vivo antitumor efficacy  6-Naphthyridin-4-one derivatives  Scaffold hopping  Structure-based drug design   Discovery, Optimization, and Evaluation of Novel Pyridin-2(1H)-one Analogues as Potent TRK Inhibitors for Cancer Treatment 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 2, 页码: 1168-1183 作者:  Xu, Zichao;  Peng, Xia;  Zhang, Renjie;  Ji, Yinchun;  You, Mengke   |  收藏  |  浏览/下载：9/0  |  提交时间：2024/02/27 Structure-based drug discovery of novel fused- pyrazolone carboxamide derivatives as potent and selective AXL inhibitors 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4918-4933 作者:  Fang, Feifei;  Dai, Yang;  Wang, Hao;  Ji, Yinchun;  Liang, Xuewu   |  收藏  |  浏览/下载：7/0  |  提交时间：2024/01/26 derivatives  Antitumor drug development  Potential AXL inhibitor  Antitumor activity  Structure-based drug design  Fused-pyrazolone carboxamide   SYK-mediated epithelial cell state is associated with response to c-Met inhibitors in c-Met-overexpressing lung cancer 期刊论文  OAI收割 SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2023, 卷号: 8, 期号: 1, 页码: 13 作者:  Zhou, Ji;  Zhang, Xu-Chao;  Xue, Shan;  Dai, Mengdi;  Wang, Yueliang   |  收藏  |  浏览/下载：12/0  |  提交时间：2023/10/17 Discovery of 3-Aminopyrazole Derivatives as New Potent and Orally Bioavailable AXL Inhibitors 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 22, 页码: 15374-15390 作者:  Chan, Shingpan;  Zhang, Yunong;  Wang, Jie;  Yu, Qiuchun;  Peng, Xia   |  收藏  |  浏览/下载：16/0  |  提交时间：2023/04/10 Anti-inflammatory and PTP1B inhibitory sesquiterpenoids from the twigs and leaves of Aglaia lawii 期刊论文  OAI收割 FITOTERAPIA, 2022, 卷号: 162, 页码: 7 作者:  Xia, Ming-Jun;  Zhang, Meng;  Li, Song-Wei;  Cai, Zhe-Fei   |  收藏  |  浏览/下载：31/0  |  提交时间：2022/11/11 Aglaia lawii  Sesquiterpenoids  Amouanglienoids A and B  X-ray diffraction  Anti-inflammatory activity  PTP1B inhibitory activity   Reduced nucleus accumbens functional connectivity in reward network and default mode network in patients with recurrent major depressive disorder 期刊论文  OAI收割 TRANSLATIONAL PSYCHIATRY, 2022, 卷号: 12, 期号: 1, 页码: 9 作者:  Ding, Yu-Dan;  Chen, Xiao;  Chen, Zuo-Bing;  Li, Le;  Li, Xue-Ying   |  收藏  |  浏览/下载：46/0  |  提交时间：2022/07/18 Genomes of leafy and leafless Platanthera orchids illuminate the evolution of mycoheterotrophy 期刊论文  OAI收割 NATURE PLANTS, 2022, 卷号: 8, 期号: 4, 页码: 373+ 作者:  Li, Ming-He;  Liu, Ke-Wei;  Li, Zhen;  Lu, Hsiang-Chia;  Ye, Qin-Liang   |  收藏  |  浏览/下载：6/0  |  提交时间：2024/03/07 Immune checkpoint inhibitor-related adverse events in lung cancer: Real-world incidence and management practices of 1905 patients in China 期刊论文  OAI收割 THORACIC CANCER, 2021 作者:  Shi, Yuequan;  Fang, Jian;  Zhou, Chengzhi;  Liu, Anwen;  Wang, Yan   |  收藏  |  浏览/下载：76/0  |  提交时间：2022/01/25 advanced lung cancer  immune checkpoint inhibitors  immune-related adverse events  real-world data   Design, Synthesis, and Pharmacological Evaluation of Biaryl-Containing PD-1/PD-L1 Interaction Inhibitors Bearing a Unique Difluoromethyleneoxy Linkage 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 22, 页码: 16687-16702 作者:  Song, Zilan;  Liu, Bo;  Peng, Xia;  Gu, Wangting;  Sun, Yiming   |  收藏  |  浏览/下载：13/0  |  提交时间：2022/06/15