BMSCs-laden gelatin/sodium alginate/carboxymethyl chitosan hydrogel for 3D bioprinting
文献类型：期刊论文
| 作者 | Huang J(黄洁); Fu H(付寒); Wang ZY(王芷莹); Meng QY(孟庆圆); Liu SM(刘素梅); Wang HR(王赫然) ; Zheng XF(郑雄飞); Dai JW(戴建武); Zhang ZJ(张智军)
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| 刊名 | RSC Advances
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| 出版日期 | 2016 |
| 卷号 | 6期号:110页码:108423-108430 |
| ISSN号 | 2046-2069 |
| 产权排序 | 3 |
| 通讯作者 | 戴建武 ; 张智军 |
| 中文摘要 | Three-dimensional (3D) bioprinting technology offers the possibility to deliver, in a defined and organized manner, scaffolding materials and living cells, and therefore holds much promise for tissue engineering and regenerative medicine. In this work, we explored the possibility of gelatin/sodium alginate/carboxymethyl chitosan (Gel/SA/CMCS) hydrogel combining with bone mesenchymal stem cells (BMSCs) for 3D bioprinting. Compared to the commonly used 3D bioprinting materials such as gelatin/sodium alginate (Gel/SA) hydrogel, the Gel/SA/CMCS hydrogel we developed shows excellent equilibrium water content, good mechanical properties, antibacterial activity, and a slow degradation rate. With this kind of material, we generated a scaffold with homogenous cell distribution. Cell viability after 3D printing showed that over 85% of the printed cells were viable at 0 and 2 days of culturing. Our work demonstrates the feasibility of mixing Gel/SA/CMCS hydrogel with stem cells for 3D bioprinting. |
| WOS标题词 | Science & Technology ; Physical Sciences |
| 类目[WOS] | Chemistry, Multidisciplinary |
| 研究领域[WOS] | Chemistry |
| 关键词[WOS] | MESENCHYMAL STEM-CELLS ; ENGINEERED CARTILAGE CONSTRUCTS ; OSTEOGENIC DIFFERENTIATION ; VALVE CONDUITS ; TISSUE ; ALGINATE ; ORGANIZATION ; FABRICATION ; SCAFFOLDS ; CULTURE |
| 收录类别 | SCI ; EI |
| 语种 | 英语 |
| WOS记录号 | WOS:000389342800036 |
| 源URL | [http://ir.sia.cn/handle/173321/19478]  |
| 专题 | 沈阳自动化研究所_机器人学研究室 |
| 推荐引用方式 GB/T 7714 | Huang J,Fu H,Wang ZY,et al. BMSCs-laden gelatin/sodium alginate/carboxymethyl chitosan hydrogel for 3D bioprinting[J]. RSC Advances,2016,6(110):108423-108430. |
| APA | Huang J.,Fu H.,Wang ZY.,Meng QY.,Liu SM.,...&Zhang ZJ.(2016).BMSCs-laden gelatin/sodium alginate/carboxymethyl chitosan hydrogel for 3D bioprinting.RSC Advances,6(110),108423-108430. |
| MLA | Huang J,et al."BMSCs-laden gelatin/sodium alginate/carboxymethyl chitosan hydrogel for 3D bioprinting".RSC Advances 6.110(2016):108423-108430. |
入库方式： OAI收割
来源：沈阳自动化研究所
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