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Scanning superlens microscopy for non-invasive large field-of-view visible light nanoscale imaging
文献类型：期刊论文
| 作者 | Wang FF(王飞飞); Liu LQ(刘连庆) ; Yu HB(于海波); Wen YD(文扬东); Yu P(于鹏); Liu Z(刘柱); Wang YC(王越超); Li WJ(李文荣)
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| 刊名 | Nature Communications
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| 出版日期 | 2016 |
| 卷号 | 7页码:1-10 |
| ISSN号 | 2041-1723 |
| 产权排序 | 1 |
| 通讯作者 | 刘连庆 ; 李文荣 |
| 中文摘要 | Nanoscale correlation of structural information acquisition with specific-molecule identification provides new insight for studying rare subcellular events. To achieve this correlation, scanning electron microscopy has been combined with super-resolution fluorescent microscopy, despite its destructivity when acquiring biological structure information. Here we propose time-efficient non-invasive microsphere-based scanning superlens microscopy that enables the large-area observation of live-cell morphology or sub-membrane structures with sub-diffraction-limited resolution and is demonstrated by observing biological and non-biological objects. This microscopy operates in both non-invasive and contact modes with B200 times the acquisition efficiency of atomic force microscopy, which is achieved by replacing the point of an atomic force microscope tip with an imaging area of microspheres and stitching the areas recorded during scanning, enabling sub-diffraction-limited resolution. Our method marks a possible path to non-invasive cell imaging and simultaneous tracking of specific molecules with nanoscale resolution, facilitating the study of subcellular events over a total cell period. |
| WOS标题词 | Science & Technology |
| 类目[WOS] | Multidisciplinary Sciences |
| 研究领域[WOS] | Science & Technology - Other Topics |
| 关键词[WOS] | ATOMIC-FORCE MICROSCOPE ; MICROSPHERE OPTICAL NANOSCOPY ; ELECTRON-MICROSCOPY ; DIFFRACTION LIMIT ; SUPERRESOLUTION MICROSCOPY ; GRAPHENE NANORIBBONS ; RESOLUTION ; ARRAYS ; CELLS ; SPECTROSCOPY |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000389537800001 |
| 源URL | [http://ir.sia.cn/handle/173321/19724]  |
| 专题 | 沈阳自动化研究所_机器人学研究室 |
| 推荐引用方式 GB/T 7714 | Wang FF,Liu LQ,Yu HB,et al. Scanning superlens microscopy for non-invasive large field-of-view visible light nanoscale imaging[J]. Nature Communications,2016,7:1-10. |
| APA | Wang FF.,Liu LQ.,Yu HB.,Wen YD.,Yu P.,...&Li WJ.(2016).Scanning superlens microscopy for non-invasive large field-of-view visible light nanoscale imaging.Nature Communications,7,1-10. |
| MLA | Wang FF,et al."Scanning superlens microscopy for non-invasive large field-of-view visible light nanoscale imaging".Nature Communications 7(2016):1-10. |
入库方式： OAI收割
来源：沈阳自动化研究所
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