Discrimination of the state of MCF-7 cells by multiple cell mechanics
文献类型：会议论文
| 作者 | Zhou FY(周富元) ; Wang WX(王文学); Liu LQ(刘连庆)
|
| 出版日期 | 2016 |
| 会议名称 | 6th Annual IEEE International Conference on Cyber Technology in Automation, Control and Intelligent Systems, IEEE-CYBER 2016 |
| 会议日期 | June 19-22, 2016 |
| 会议地点 | Chengdu, China |
| 关键词 | cell mechanics MCF-7 cells young’s modulus energy dissipation |
| 页码 | 468-473 |
| 通讯作者 | 王文学 ; 刘连庆 |
| 中文摘要 | Cell mechanics indicating the state of cell play an important role in critical activities of the cells. However in recent cell mechanics research, most of researchers only considered the young's modulus and energy dissipation is seldom considered. The existing method of the computation of young's modulus can't also make sure the distance between experimental indentation curve and the theory experimental indentation curve is small. To solve the problems described above, an optimization method of computation of young's modulus has been proposed and an experiment has been carried out. In the experiment force curves were obtained from the MCF-7 cells which has been treated with different concentrations (0ug/ml, 50ug/ml, 100ug/ml, 150ug/ml, 200ug/ml) of resveratrol for 36 hours. Young's modulus and energy dissipation could be obtained from the force curves. The experiment results not only shown that compared with the existing method the proposed method has its superiority in the computation of young's modulus, but also indicated that there is a necessity of considering both Young's modulus and energy dissipation. The results provide an effective method for the computation of cell mechanics and lay a foundation for the drug selection and personalized treatment of diseases. |
| 收录类别 | EI ; CPCI（ISTP） |
| 产权排序 | 1 |
| 会议录 | 6th Annual IEEE International Conference on Cyber Technology in Automation, Control and Intelligent Systems, IEEE-CYBER 2016
 |
| 会议录出版者 | IEEE |
| 会议录出版地 | Piscataway, NJ, USA |
| 语种 | 英语 |
| ISSN号 | 2379-7711 |
| ISBN号 | 978-1-5090-2732-3 |
| WOS记录号 | WOS:000389835200087 |
| 源URL | [http://ir.sia.cn/handle/173321/19301]  |
| 专题 | 沈阳自动化研究所_机器人学研究室 |
| 推荐引用方式 GB/T 7714 | Zhou FY,Wang WX,Liu LQ. Discrimination of the state of MCF-7 cells by multiple cell mechanics[C]. 见:6th Annual IEEE International Conference on Cyber Technology in Automation, Control and Intelligent Systems, IEEE-CYBER 2016. Chengdu, China. June 19-22, 2016. |
入库方式： OAI收割
来源：沈阳自动化研究所
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