A novel approach to optimize combinatory drugs using Markov chain
文献类型：会议论文
| 作者 | Wang B(王博); Wang WX(王文学) ; Wang YC(王越超); Liu LQ(刘连庆)
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| 出版日期 | 2016 |
| 会议名称 | 2016 IEEE 11th Annual International Conference on Nano/Micro Engineered and Molecular Systems (NEMS) |
| 会议日期 | April 17-20, 2016 |
| 会议地点 | Sendai, Japan |
| 页码 | 18-23 |
| 通讯作者 | 王文学 ; 刘连庆 |
| 中文摘要 | Combinatory drugs are often used in clinical medications for treating some complex diseases such as cancer, diabetes, etc. An extreme challenge in combinatory therapy is that the number of combinations will increase exponentially as the types of drugs increase, which makes it very difficult to choose the optimal concentration. In this paper, we present a new algorithm based on the stationary distribution of Markov chain to optimize combinatory drugs. We evaluated the new algorithm by comparing its performance with the other two stochastic algorithms, the Gur Game algorithm and the modified Gur Game algorithm. Numerical simulations clearly show that the algorithm based on Markov chain has a better performance than these two stochastic algorithms, in terms of both reliability and efficiency. This work provides a general method for the combinatorial optimization problem, and it is meaningful for clinical combinatory therapy. |
| 收录类别 | EI ; CPCI（ISTP） |
| 产权排序 | 1 |
| 会议录 | Proceedings of the 11th IEEE Annual International Conference on Nano/Micro Engineered and Molecular Systems (NEMS)
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| 会议录出版者 | IEEE |
| 会议录出版地 | New York |
| 语种 | 英语 |
| ISBN号 | 978-1-5090-1948-9 |
| WOS记录号 | WOS:000391893400005 |
| 源URL | [http://ir.sia.cn/handle/173321/19568]  |
| 专题 | 沈阳自动化研究所_机器人学研究室 |
| 推荐引用方式 GB/T 7714 | Wang B,Wang WX,Wang YC,et al. A novel approach to optimize combinatory drugs using Markov chain[C]. 见:2016 IEEE 11th Annual International Conference on Nano/Micro Engineered and Molecular Systems (NEMS). Sendai, Japan. April 17-20, 2016. |
入库方式： OAI收割
来源：沈阳自动化研究所
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