Kwong-Li probes: Novel nano-probes for biological dissection and injection
文献类型:会议论文
作者 | Kwong, C.C.H.; Lai, K.W.C.; Yan, Ruiguang; Li WJ(李文荣)![]() |
出版日期 | 2003 |
会议名称 | 2003 IEEE/ASME International Conference on Advanced Intelligent Mechatronics, AIM 2003 |
会议日期 | July 20-24, 2003 |
会议地点 | Kobe, Japan |
关键词 | Sacrificial Boundary Etching SNOM Tips Nan0 Tips Kwong-Li Probes Kowng-Li Method |
页码 | 897-901 |
通讯作者 | 李文荣 |
中文摘要 | We recently discovered a very fast and reliable single-step etching process to fabricate tiny-angled (<2.7°) fiber probe tips, which is less complex and yields finer tips than other available multiple-step sharp-tip (e.g., SNOM tips) fabrication processes. The process is named as Kwong-Li's (KL) Method. As the probe profile depends highly on the interfacial meniscus of the etchant, by means of our sacrificial boundary etching technique, in which we introduced glass tubing as etching barriers, probes with very sharp tips and long tapers were formed. Using p-xylene as organic solvent and hydrofluoric acid as etchant, we succeeded in shaping optical fibers (with initial fiber diameter of 125 μm) into sharp tips with angles ranging front <2.7-9.7°, with nanoscale tip diameter of <1μm. By adjusting the initial etchant height in the tubing, final tip angles can be controlled. With their nanometric tips, these sharp probes will be useful for various scanning probe microscopy applications and could potentially be used as surgical tools for micro cellular surgery, i.e., we have already shown that KL probes will penetrate through cell membranes with less mechanical resistance than conventional pipettes and probes made by Turner's Method. The fabrication process of KL probes and experimental results from using KL probes to probe cells are presented in this paper. |
收录类别 | EI ; CPCI(ISTP) |
产权排序 | 2 |
会议主办者 | ASME Dynamic Systems and Control Division (DSC); IEEE Industrial Electronics Society (IES); IEEE Robotics and Automation Society (RAS) |
会议录 | IEEE/ASME International Conference on Advanced Intelligent Mechatronics, AIM
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会议录出版者 | Institute of Electrical and Electronics Engineers Inc. |
语种 | 英语 |
ISBN号 | 0-7803-7759-1 |
WOS记录号 | WOS:000185624100151 |
源URL | [http://ir.sia.cn/handle/173321/19999] ![]() |
专题 | 沈阳自动化研究所_机器人学研究室 |
推荐引用方式 GB/T 7714 | Kwong, C.C.H.,Lai, K.W.C.,Yan, Ruiguang,et al. Kwong-Li probes: Novel nano-probes for biological dissection and injection[C]. 见:2003 IEEE/ASME International Conference on Advanced Intelligent Mechatronics, AIM 2003. Kobe, Japan. July 20-24, 2003. |
入库方式: OAI收割
来源:沈阳自动化研究所
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