Modeling and analysis of mechanical properties of single cells
文献类型：会议论文
| 作者 | Wang B(王博); Wang WX(王文学) ; Wang YC(王越超); Liu LQ(刘连庆)
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| 出版日期 | 2016 |
| 会议名称 | 10th IEEE International Conference on Nano/Molecular Medicine and Engineering, NANOMED 2016 |
| 会议日期 | October 30 - November 2, 2016 |
| 会议地点 | Macau, China |
| 关键词 | single cell dynamic model mechanical properties principal component analysis atomic force microscopy viscoelasticity |
| 页码 | 51-54 |
| 通讯作者 | 王文学 ; 刘连庆 |
| 中文摘要 | Cells can be regarded as a complex network, which contains thousands of criss-cross signal pathways. The mechanical properties of a cell reflect the structure and composition of its cytoskeleton and are closely related to the cellular biological functions and physiological activities. In this study, we develop a dynamical model with cellular viscoelasticity properties as the system parameters to describe the stress-relaxation phenomenon of a single cell under the indentation of atomic force microscope (AFM). The system order and parameters were identified and analyzed. The parameters identified with this model represent the cellular mechanical elasticity and viscosity respectively and can be used to classify cell types and discriminate cellular state. |
| 收录类别 | EI |
| 产权排序 | 1 |
| 会议录 | 2016 IEEE 10th International Conference on Nano/Molecular Medicine and Engineering, NANOMED 2016
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| 会议录出版者 | IEEE Computer Society |
| 会议录出版地 | Piscataway, NJ, USA |
| 语种 | 英语 |
| ISSN号 | 2159-6964 |
| ISBN号 | 978-1-5090-4675-1 |
| 源URL | [http://ir.sia.cn/handle/173321/20428]  |
| 专题 | 沈阳自动化研究所_机器人学研究室 |
| 推荐引用方式 GB/T 7714 | Wang B,Wang WX,Wang YC,et al. Modeling and analysis of mechanical properties of single cells[C]. 见:10th IEEE International Conference on Nano/Molecular Medicine and Engineering, NANOMED 2016. Macau, China. October 30 - November 2, 2016. |
入库方式： OAI收割
来源：沈阳自动化研究所
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