Detecting the Micro/nano Physical Properties of Single Lymphoma Cells with Atomic Force Microscopy
文献类型：会议论文
| 作者 | Liu LQ(刘连庆) ; Wang B(王博); Li M(李密); Wei FN(魏发南); Liu B(刘斌)
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| 出版日期 | 2017 |
| 会议名称 | 2017 7th International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO) |
| 会议日期 | Augest 7-11, 2017 |
| 会议地点 | Shanghai, CHINA |
| 关键词 | Atomic force microscopy Lymphoma Image Elasticity Force curve |
| 页码 | 250-253 |
| 通讯作者 | Liu B(刘斌) |
| 中文摘要 | Non-Hodgkin's lymphoma (NHL) is the most common adult hematological cancer. With the advent of combination therapy of chemotherapy and the monoclonal anti-CD20 antibody Rituximab, the substantial advancement in the treatment of B-cell malignancies has been achieved. In the clinical treatment of NHL, however, there are still many patients who are not sensitive to the therapy of rituximab. Hence investigating the interactions between rituximab and lymphoma cells is crucial for us to understand the actions of rituximab and design drugs with better efficacies. Traditional biochemical methods for cell detection require the various pretreatments of the cell, destroying the structures of cells. This paper uses atomic force microscopy (AFM) to label-free characterize the micro/nano physical properties of single lymphoma cells, including cell morphology, cell elasticity, and molecular interactions on the cell surface. The study improved our understanding of the rituximab actions. |
| 收录类别 | EI ; CPCI（ISTP） |
| 产权排序 | 1 |
| 会议主办者 | Natl Nat Sci Fdn China, Minist Sci & Technol Peoples Republic of China, Minist Educ Peoples Republic of China, European Commiss, Res Execut Agcy, Jilin Provincial Sci & Technol Dept, IFToMM, Int Soc Nanomfg |
| 会议录 | 2017 IEEE INTERNATIONAL CONFERENCE ON MANIPULATION, MANUFACTURING AND MEASUREMENT ON THE NANOSCALE (3M-NANO)
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| 会议录出版者 | IEEE |
| 会议录出版地 | NEW YORK |
| 语种 | 英语 |
| ISSN号 | 2373-5422 |
| ISBN号 | 978-1-5386-1081-7 |
| WOS记录号 | WOS:000426927300053 |
| 源URL | [http://ir.sia.cn/handle/173321/21654]  |
| 专题 | 沈阳自动化研究所_机器人学研究室 |
| 作者单位 | 1.State Key Laboratory of Robotics, Shenyang Institute of Automation, Chinese Academy of Sciences 2.School of Mechanical Engineering and Automation, Fuzhou University |
| 推荐引用方式 GB/T 7714 | Liu LQ,Wang B,Li M,et al. Detecting the Micro/nano Physical Properties of Single Lymphoma Cells with Atomic Force Microscopy[C]. 见:2017 7th International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO). Shanghai, CHINA. Augest 7-11, 2017. |
入库方式： OAI收割
来源：沈阳自动化研究所
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