Biological activity and LC-MS profiling of ethyl acetate extracts from Nitraria sibirica (Pall.) fruits
文献类型:期刊论文
作者 | Gu, DY (Gu, Dongyu)[ 1,2 ]; Yang, Y (Yang, Yi)[ 1 ]; Bakri, M (Bakri, Mahinur)[ 1 ]; Chen, QB (Chen, Qibin)[ 1 ]; Aisa, HA (Aisa, Haji Akber)[ 1 ] |
刊名 | NATURAL PRODUCT RESEARCH |
出版日期 | 2018 |
卷号 | 32期号:17页码:2054-2057 |
ISSN号 | 1478-6419 |
关键词 | Nitraria Sibirica Pall Protein Tyrosine Phosphatase 1b Inhibitory Antioxidant Phenolic Constituents Lc-qtof-ms Ms |
DOI | 10.1080/14786419.2017.1359175 |
英文摘要 | Nitraria sibirica is a traditional Uighur medicine. This study was undertaken to investigate the bioactivity of N. sibirica fruit extract and to evaluate their chemical compositions. The ethyl acetate extract from N. sibirica fruits exhibited the potential antioxidant activity (SC50=30.17 +/- 0.06g/mL) and protein tyrosine phosphatase 1B inhibitory activity (IC50=7.15 +/- 0.03g/mL) in vitro. In order to investigate the active constituents in this extract, a LC-QTOF-MS/MS method was developed and established. A total of 28 compounds including seven cinnamic acids, nine benzoic acids and 12 flavonoids were identified or partially characterised according to the accurate mass and the characteristic fragment ions at low and high collision energy. Most of them were reported for the first time in this plant. Phytochemical profiles of the active extract will help the development and utilisation of N. sibirica in food and medicine. |
WOS记录号 | WOS:000440606000008 |
源URL | [http://ir.xjipc.cas.cn/handle/365002/5635] |
专题 | 新疆理化技术研究所_省部共建新疆特有药用资源利用重点实验室 新疆理化技术研究所_资源化学研究室 |
通讯作者 | Aisa, HA (Aisa, Haji Akber)[ 1 ] |
作者单位 | 1.Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, Key Lab Plant Resources & Chem Arid Zone, Urumqi, Peoples R China 2.Dalian Ocean Univ, Sch Marine Sci & Environm Engn, Dalian, Peoples R China |
推荐引用方式 GB/T 7714 | Gu, DY ,Yang, Y ,Bakri, M ,et al. Biological activity and LC-MS profiling of ethyl acetate extracts from Nitraria sibirica (Pall.) fruits[J]. NATURAL PRODUCT RESEARCH,2018,32(17):2054-2057. |
APA | Gu, DY ,Yang, Y ,Bakri, M ,Chen, QB ,&Aisa, HA .(2018).Biological activity and LC-MS profiling of ethyl acetate extracts from Nitraria sibirica (Pall.) fruits.NATURAL PRODUCT RESEARCH,32(17),2054-2057. |
MLA | Gu, DY ,et al."Biological activity and LC-MS profiling of ethyl acetate extracts from Nitraria sibirica (Pall.) fruits".NATURAL PRODUCT RESEARCH 32.17(2018):2054-2057. |
入库方式: OAI收割
来源:新疆理化技术研究所
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