Investigation and Application of Amphoteric alpha-Amino Aldehyde: An in Situ Generated Species Based on Heyns Rearrangement
文献类型：期刊论文
| 作者 | Wang, YW; Tang, L; Li, GX; Tang, Z (reprint author), Chinese Acad Sci, Chengdu Inst Biol, Nat Prod Res Ctr, 9 Sect 4,Renmin Nan Rd, Chengdu 610041, Peoples R China.; Tang, Z; Zhao, G; Liu, HX |
| 刊名 | ORGANIC LETTERS
 |
| 出版日期 | 2016 |
| 卷号 | 18期号:18页码:4526-4529 |
| DOI | 10.1021/acs.orglett.6b02133 |
| 产权排序 | 1 |
| 文献子类 | Article |
| 英文摘要 | In situ generation of the reactive amphoteric a amino aldehyde with simple alpha-hydroxy ketones and phenyl amine-via Heyns rearrangement was proven to be feasible. Metal-free domino reactions based on this reactive intermediate were effectively used to afford important N-heterocycles including polysubstituted pyrroles, indoles, and quinoxalines conveniently. A simple starting material, water as the only byproduct, and diversity of the useful products will make this method greatly attractive for pharmaceutics. |
| 学科主题 | Chemistry |
| 语种 | 英语 |
| 资助机构 | National Science Foundation of China [21402188] ; National Science Foundation of China [21402188] ; National Science Foundation of China [21402188] ; National Science Foundation of China [21402188] |
| 源URL | [http://210.75.237.14/handle/351003/28179]  |
| 专题 | 成都生物研究所_天然产物研究 |
| 通讯作者 | Li, GX; Tang, Z (reprint author), Chinese Acad Sci, Chengdu Inst Biol, Nat Prod Res Ctr, 9 Sect 4,Renmin Nan Rd, Chengdu 610041, Peoples R China. |
| 推荐引用方式 GB/T 7714 | Wang, YW,Tang, L,Li, GX,et al. Investigation and Application of Amphoteric alpha-Amino Aldehyde: An in Situ Generated Species Based on Heyns Rearrangement[J]. ORGANIC LETTERS,2016,18(18):4526-4529. |
| APA | Wang, YW.,Tang, L.,Li, GX.,Tang, Z .,Tang, Z.,...&Liu, HX.(2016).Investigation and Application of Amphoteric alpha-Amino Aldehyde: An in Situ Generated Species Based on Heyns Rearrangement.ORGANIC LETTERS,18(18),4526-4529. |
| MLA | Wang, YW,et al."Investigation and Application of Amphoteric alpha-Amino Aldehyde: An in Situ Generated Species Based on Heyns Rearrangement".ORGANIC LETTERS 18.18(2016):4526-4529. |
入库方式： OAI收割
来源：成都生物研究所
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