First example of an organocatalytic asymmetric Mannich reaction between aldimines of glycinates and sulphonyl imines
文献类型：期刊论文
| 作者 | He, MG; Tang, Z (reprint author), Chinese Acad Sci, Chengdu Inst Biol, Nat Prod Res Ctr, Chengdu 610041, Sichuan, Peoples R China.; Zhao, G (reprint author), Sichuan Univ, Coll Chem Engn, Chengdu 610064, Peoples R China.; Tang, Z; Zhao, G; Wang, YW; Li, GX; Wu, L |
| 刊名 | CANADIAN JOURNAL OF CHEMISTRY
 |
| 出版日期 | 2016 |
| 卷号 | 94期号:9页码:769-772 |
| 关键词 | Organocatalyst Aldimine Glycinates Sulphonyl Imine Chiral Guanidine |
| DOI | 10.1139/cjc-2016-0089 |
| 产权排序 | 2 |
| 文献子类 | Article |
| 英文摘要 | The catalytic enantioselective Mannich-type reaction between glycinate Schiff base and imines has been one of the most efficient routes for accessing alpha,beta-diamino acids. However, the glycinate Schiff bases used in the references were almost ketimines. Only several examples of aldimines were used in the presence of metal catalyst. We developed the first example of an asymmetric direct Mannich reaction using aldimines of glycinates instead of ketimines of glycinates. The reaction was well catalyzed by chiral guanidine with high yield (up to 92%) and moderate stereoselectivity (up to 65%). |
| 学科主题 | Chemistry |
| 语种 | 英语 |
| 资助机构 | National Sciences Foundation of China [21402188] ; National Sciences Foundation of China [21402188] ; National Sciences Foundation of China [21402188] ; National Sciences Foundation of China [21402188] |
| 源URL | [http://210.75.237.14/handle/351003/28181]  |
| 专题 | 成都生物研究所_天然产物研究 |
| 通讯作者 | Tang, Z (reprint author), Chinese Acad Sci, Chengdu Inst Biol, Nat Prod Res Ctr, Chengdu 610041, Sichuan, Peoples R China.; Zhao, G (reprint author), Sichuan Univ, Coll Chem Engn, Chengdu 610064, Peoples R China. |
| 推荐引用方式 GB/T 7714 | He, MG,Tang, Z ,Zhao, G ,et al. First example of an organocatalytic asymmetric Mannich reaction between aldimines of glycinates and sulphonyl imines[J]. CANADIAN JOURNAL OF CHEMISTRY,2016,94(9):769-772. |
| APA | He, MG.,Tang, Z .,Zhao, G .,Tang, Z.,Zhao, G.,...&Wu, L.(2016).First example of an organocatalytic asymmetric Mannich reaction between aldimines of glycinates and sulphonyl imines.CANADIAN JOURNAL OF CHEMISTRY,94(9),769-772. |
| MLA | He, MG,et al."First example of an organocatalytic asymmetric Mannich reaction between aldimines of glycinates and sulphonyl imines".CANADIAN JOURNAL OF CHEMISTRY 94.9(2016):769-772. |
入库方式： OAI收割
来源：成都生物研究所
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