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Chinese Academy of Sciences Institutional Repositories Grid
The single-nucleocapsid nucleopolyhedrovirus of buzura suppressaria encodes a p10 protein

文献类型:期刊论文

作者van Oers, MM; Hu, ZH; Arif, BM; van Strien, EA; van Lent, JWM; Vlak, JM
刊名Journal of general virology
出版日期1998-06-01
卷号79页码:1553-1562
ISSN号0022-1317
通讯作者Vlak, jm()
英文摘要The p10 gene of buzura suppressaria single-nucleocapsid nucleopolyhedrovirus (busunpv) was identified by virtue of its localization downstream from the autographa californica (ac) mnpv p26 homologue, the busunpv p10 gene encodes a protein of 94 amino acids. the amino acid sequence contains domains characteristic of baculovirus p10 proteins, e.g. a coiled-coil domain, a proline-rich motif and a positively charged c terminus. the highest amino acid homologies were found with the spodoptera littoralis (spli) npv and spodoptera exigua (se) mnpv p10 proteins. an acmnpv recombinant expressing the busunpv p10 formed fibrillar structures in the cytoplasm of spodoptera frugiperda cells, busunpv p10 could not fully replace acmnpv p10 in its nuclear disintegration function, since polyhedra were not efficiently liberated from infected cells late in infection. the busunpv p26 gene encodes a protein of 263 amino acid residues with 70% amino acid similarity with semnpv p26. downstream of the busunpv p10 gene, the gene for the occlusion-derived virus protein odvp-6e is located. this is unlike the situation in many other npvs, including semnpv, where the p10 gene neighbours the p74 gene. the data presented here suggest that although the p10 gene is not conserved in sequence, evolutionary pressure preserves the structure of p10 and hence its function, these data also indicate that all npvs, mnpvs as well as snpvs, contain this gene.
WOS关键词NUCLEAR POLYHEDROSIS-VIRUS ; NUCLEOTIDE-SEQUENCE ; BACULOVIRUS VECTOR ; ENVELOPE PROTEIN ; GENE ; EXPRESSION ; TRANSCRIPTION ; REGION ; GENOME ; P74
WOS研究方向Biotechnology & Applied Microbiology ; Virology
WOS类目Biotechnology & Applied Microbiology ; Virology
语种英语
WOS记录号WOS:000073887700030
出版者SOC GENERAL MICROBIOLOGY
URI标识http://www.irgrid.ac.cn/handle/1471x/2376040
专题武汉病毒研究所
通讯作者Vlak, JM
作者单位1.Agr Univ Wageningen, Dept Virol, NL-6709 PD Wageningen, Netherlands
2.Univ Utrecht, Dept Mol Cell Biol, NL-3584 CH Utrecht, Netherlands
3.Chinese Acad Sci, Wuhan Inst Virol, Wuhan, Peoples R China
4.Forestry Canada, Inst Forest Pest Management, Sault St Marie, ON P6A 5M7, Canada
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GB/T 7714
van Oers, MM,Hu, ZH,Arif, BM,et al. The single-nucleocapsid nucleopolyhedrovirus of buzura suppressaria encodes a p10 protein[J]. Journal of general virology,1998,79:1553-1562.
APA van Oers, MM,Hu, ZH,Arif, BM,van Strien, EA,van Lent, JWM,&Vlak, JM.(1998).The single-nucleocapsid nucleopolyhedrovirus of buzura suppressaria encodes a p10 protein.Journal of general virology,79,1553-1562.
MLA van Oers, MM,et al."The single-nucleocapsid nucleopolyhedrovirus of buzura suppressaria encodes a p10 protein".Journal of general virology 79(1998):1553-1562.

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来源:武汉病毒研究所

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