Crystallization and preliminary crystallographic studies of an antitumour lectin from the edible mushroom agrocybe aegerita
文献类型:期刊论文
作者 | Yang, N; Liang, Y; Xiang, Y; Zhang, Y; Sun, H; Wang, DC |
刊名 | Protein and peptide letters
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出版日期 | 2005-10-01 |
卷号 | 12期号:7页码:705-707 |
关键词 | Lectin Mushroom Antitumour Apoptosis Dnase activity Crystallization |
ISSN号 | 0929-8665 |
通讯作者 | Wang, dc() |
英文摘要 | An antitumour lectin named aal has. been purified from the fruiting body of edible mushroom agrocybe aegerita. in addition to having a distinct bioactivity, aal shows strong inhibition effects on human and mouse tumour cells. it has been shown that aal exerts its antitumour effects via apoptosis-induction. aal and aal-lactose complex have been crystallized and their diffraction data were collected with resolution of 2.6 angstrom and 3.0 angstrom, respectively. both crystals belong to space group p 6122 with unit cell parameters a = 123.98 angstrom, b = 123.98 angstrom, c = 56.86 angstrom, alpha = 0=90 degrees, gamma = 120 degrees and a = 123.69 angstrom, b = 123.69 angstrom, c = 56.64 angstrom, alpha = beta=90 degrees, gamma = 120 degrees, respectively. |
WOS关键词 | GALECTINS ; MYCELIA ; FAMILY |
WOS研究方向 | Biochemistry & Molecular Biology |
WOS类目 | Biochemistry & Molecular Biology |
语种 | 英语 |
WOS记录号 | WOS:000231958900017 |
出版者 | BENTHAM SCIENCE PUBL LTD |
URI标识 | http://www.irgrid.ac.cn/handle/1471x/2377079 |
专题 | 中国科学院大学 |
通讯作者 | Wang, DC |
作者单位 | 1.Wuhan Univ, Coll Life Sci, State Key Lab Virol, Wuhan 430072, Peoples R China 2.Chinese Acad Sci, Inst Biophys, Ctr Struct & Mol Biol, Beijing 100101, Peoples R China 3.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China |
推荐引用方式 GB/T 7714 | Yang, N,Liang, Y,Xiang, Y,et al. Crystallization and preliminary crystallographic studies of an antitumour lectin from the edible mushroom agrocybe aegerita[J]. Protein and peptide letters,2005,12(7):705-707. |
APA | Yang, N,Liang, Y,Xiang, Y,Zhang, Y,Sun, H,&Wang, DC.(2005).Crystallization and preliminary crystallographic studies of an antitumour lectin from the edible mushroom agrocybe aegerita.Protein and peptide letters,12(7),705-707. |
MLA | Yang, N,et al."Crystallization and preliminary crystallographic studies of an antitumour lectin from the edible mushroom agrocybe aegerita".Protein and peptide letters 12.7(2005):705-707. |
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来源:中国科学院大学
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