Preparation and characteristics of a calcium magnesium silicate (bredigite) bioactive ceramic
文献类型:期刊论文
作者 | Wu, CT; Chang, JA; Wang, JY; Ni, SY; Zhai, WY |
刊名 | Biomaterials
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出版日期 | 2005-06-01 |
卷号 | 26期号:16页码:2925-2931 |
关键词 | Bredigite Bioactivity Hydroxyapatite Osteoblasts Biocompatibility |
ISSN号 | 0142-9612 |
DOI | 10.1016/j.biomaterials.2004.09.019 |
通讯作者 | Chang, ja() |
英文摘要 | In this study, new bredigite (ca7mgsi4o16) ceramics were prepared by sintering sol-gel-derived bredigite powder compacts at 1350degreesc for 8h. the bending strength, fracture toughness and young's modulus were about 156 mpa, 1.57 mpa m(1/2) and 43 gpa, respectively. the in vitro bioactivity of the bredigite ceramics was evaluated by investigating the apatite-formation ability in simulated body fluid (sbf) and the effect of ionic products from bredigite dissolution on the mouse fibroblasts cell line l929. in addition, the in vitro biocompatibility of the bredigite ceramics was evaluated by osteoblasts adhesion and proliferation assay. the results showed that bredigite ceramics could induce hap formation in sbf. the products from bredigite dissolution significantly promoted cell growth at a certain concentration range. furthermore, osteoblasts adhered and spread well on bredigite ceramics, and osteoblasts proliferation on bredigite ceramics was obvious. (c) 2004 elsevier ltd. all rights reserved. |
WOS关键词 | SIMULATED BODY-FLUID ; IN-VITRO ; BIOCERAMICS ; DIOPSIDE ; GLASSES ; POWDERS ; SURFACE ; CASIO3 ; CELLS |
WOS研究方向 | Engineering ; Materials Science |
WOS类目 | Engineering, Biomedical ; Materials Science, Biomaterials |
语种 | 英语 |
WOS记录号 | WOS:000226675500014 |
出版者 | ELSEVIER SCI LTD |
URI标识 | http://www.irgrid.ac.cn/handle/1471x/2377541 |
专题 | 中国科学院大学 |
通讯作者 | Chang, JA |
作者单位 | 1.Chinese Acad Sci, Shanghai Inst Ceram, Biomat & Tissue Engn Res Ctr, Shanghai 200050, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100864, Peoples R China 3.E China Normal Univ, Sch Biol Sci, Shanghai 200062, Peoples R China |
推荐引用方式 GB/T 7714 | Wu, CT,Chang, JA,Wang, JY,et al. Preparation and characteristics of a calcium magnesium silicate (bredigite) bioactive ceramic[J]. Biomaterials,2005,26(16):2925-2931. |
APA | Wu, CT,Chang, JA,Wang, JY,Ni, SY,&Zhai, WY.(2005).Preparation and characteristics of a calcium magnesium silicate (bredigite) bioactive ceramic.Biomaterials,26(16),2925-2931. |
MLA | Wu, CT,et al."Preparation and characteristics of a calcium magnesium silicate (bredigite) bioactive ceramic".Biomaterials 26.16(2005):2925-2931. |
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来源:中国科学院大学
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