The self-setting properties and in vitro bioactivity of tricalcium silicate
文献类型：期刊论文
| 作者 | Zhao, WY; Wang, JY; Zhai, WY; Wang, Z; Chang, J |
| 刊名 | Biomaterials
 |
| 出版日期 | 2005-11-01 |
| 卷号 | 26期号:31页码:6113-6121 |
| 关键词 | Tricalcium silicate Injectability Self-setting Bioactivity Cell proliferation |
| ISSN号 | 0142-9612 |
| DOI | 10.1016/j.biomaterials.2005.04.025 |
| 通讯作者 | Chang, j() |
| 英文摘要 | In this study, tricalcium silicate (ca3sio5), as a new promising injectable bioactive material, was employed to investigate its physical and chemical properties for an injectable bioactive cement filler. the workable ca3sio5 pastes with a liquid to powder (l/p) ratio of 0.8-1.2 ml g(-1) could be injected for 15-60min (nozzle diameter 2.0mm). the setting process yielded cellular structures with compressive strength of 6.4-20.2 mpa after 2-28 days. the in vitro bioactivity of ca3sio5 paste was investigated by soaking in simulated body fluid (sbf) for various periods. the result showed that the ca3sio5 paste could induce hydroxyapatite (ha) formation and dissolve slowly in sbf. the result of indirect cytotoxicity evaluation indicated that ca3sio5 paste had a stimulatory effect on cell growth in a certain concentration range. the exothermic process showed that ca3sio5 had lower heat evolution rate during the hydration as compared to calcium phosphate cement (cpc). our results indicated that ca3sio5 paste was bioactive and dissolvable, and it is a progressive candidate for further investigation as injectable tissue repairing substitute. (c) 2005 elsevier ltd. all rights reserved. |
| WOS关键词 | CALCIUM-PHOSPHATE CEMENTS ; BONE CEMENTS ; CERAMICS ; HYDRATION ; BEHAVIOR |
| WOS研究方向 | Engineering ; Materials Science |
| WOS类目 | Engineering, Biomedical ; Materials Science, Biomaterials |
| 语种 | 英语 |
| WOS记录号 | WOS:000230975100003 |
| 出版者 | ELSEVIER SCI LTD |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2377568 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Chang, J |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Inst Ceram, Biomat & Tissue Engn Res Ctr, Shanghai 200050, Peoples R China 2.Chinese Acad Sci, Grad Sch, Shanghai 200050, Peoples R China 3.E China Normal Univ, Sch Biol Sci, Shanghai 200062, Peoples R China 4.Chinese Acad Sci, Analysis & Testing Ctr Inorgan Mat, Shanghai 200050, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhao, WY,Wang, JY,Zhai, WY,et al. The self-setting properties and in vitro bioactivity of tricalcium silicate[J]. Biomaterials,2005,26(31):6113-6121. |
| APA | Zhao, WY,Wang, JY,Zhai, WY,Wang, Z,&Chang, J.(2005).The self-setting properties and in vitro bioactivity of tricalcium silicate.Biomaterials,26(31),6113-6121. |
| MLA | Zhao, WY,et al."The self-setting properties and in vitro bioactivity of tricalcium silicate".Biomaterials 26.31(2005):6113-6121. |
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来源：中国科学院大学
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