The preparation and characterisation of a novel siloxane biomaterial
文献类型：期刊论文
| 作者 | Cao, Shunsheng; Deng, Xiaobo; Liu, Bailing; Luo, Rong; Chen, Hualing |
| 刊名 | Polymers & polymer composites
 |
| 出版日期 | 2006 |
| 卷号 | 14期号:8页码:833-840 |
| ISSN号 | 0967-3911 |
| 通讯作者 | Cao, shunsheng(sscaochem@hotmail.com) |
| 英文摘要 | It is well known that polysiloxane interacts strongly with proteins and has been shown to adsorb significant quantities of protein due to its strong hydrophobicity, which often promotes conformational and orientational changes in the adsorbed proteins so as to decrease their biocompatibility. therefore, the control of protein adsorption to biomaterials and the preparation of suitable siloxane biomaterials become necessary and significant for the actual application. in this paper, a novel siloxane biomaterial (siloxane microspheres) was prepared by dispersion polymerization under kinetically controlled conditions. and then, the siloxane biomaterial was characterized by particle size analyser, x-ray photoelectron spectroscopy (xps) and static contact angle. the siloxane microspheres were used as the matrix, and bovine serum albumin (bsa) as the template protein, the adsorption has been investigated. the study shows that the amount of protein adsorption (bsa) is higher in the prescence of siloxane monomer than than in its absence, and the effects become more evident with the increase in the contents of siloxane monomer. this indicates that its hydrophobicity of siloxane microspheres can be shepherded through the amount of siloxane monomer added. |
| WOS关键词 | PROTEIN ADSORPTION ; POLYMERIC BIOMATERIALS ; SURFACE MODIFICATION ; IMMOBILIZATION ; COPOLYMERS ; INTERFACES ; SUPPORTS ; FORCES ; SHELL |
| WOS研究方向 | Materials Science ; Polymer Science |
| WOS类目 | Materials Science, Characterization & Testing ; Materials Science, Composites ; Polymer Science |
| 语种 | 英语 |
| WOS记录号 | WOS:000242907700008 |
| 出版者 | RAPRA TECHNOLOGY LTD |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2378699 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Cao, Shunsheng |
| 作者单位 | 1.Jiangsu Univ, Sch Mat Sci & Engn, Zhenjiang 212013, Peoples R China 2.CAS, Grad Sch, Chengdu Inst Organ Chem, Chengdu 610041, Peoples R China |
| 推荐引用方式 GB/T 7714 | Cao, Shunsheng,Deng, Xiaobo,Liu, Bailing,et al. The preparation and characterisation of a novel siloxane biomaterial[J]. Polymers & polymer composites,2006,14(8):833-840. |
| APA | Cao, Shunsheng,Deng, Xiaobo,Liu, Bailing,Luo, Rong,&Chen, Hualing.(2006).The preparation and characterisation of a novel siloxane biomaterial.Polymers & polymer composites,14(8),833-840. |
| MLA | Cao, Shunsheng,et al."The preparation and characterisation of a novel siloxane biomaterial".Polymers & polymer composites 14.8(2006):833-840. |
入库方式： iSwitch采集
来源：中国科学院大学
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。