Synthesis of 3-alkyl-1h-quinolin-2-ones via palladium-catalyzed intramolecular cyclization of benzyl halides and alpha,beta-unsaturated amides
文献类型：期刊论文
| 作者 | Liu, Zhangqin1,2; Shi, Changqing1,2; Chen, Yuanwei1 |
| 刊名 | Synlett
 |
| 出版日期 | 2008-07-01 |
| 期号 | 11页码:1734-1736 |
| 关键词 | Palladium Cyclization Benzyl halides Electron-deficient olefins Quinolinone |
| ISSN号 | 0936-5214 |
| DOI | 10.1055/s-2008-1077875 |
| 通讯作者 | Chen, yuanwei(chenyw@cioc.ac.cn) |
| 英文摘要 | An efficient synthesis of 3-alkyl-1h-quinolin-2-ones was achieved in high yield (up to 91%) via pd(2)(dba)(3)-catalyzed intramolecular cyclization of benzyl halides and electron-deficient olefins, followed by treatment with dbu. |
| WOS关键词 | CROSS-COUPLING REACTIONS ; SONOGASHIRA REACTIONS ; TUBERCULOSIS ; VINYLATION ; OLEFINS ; ROUTE ; DRUG |
| WOS研究方向 | Chemistry |
| WOS类目 | Chemistry, Organic |
| 语种 | 英语 |
| WOS记录号 | WOS:000258595100031 |
| 出版者 | GEORG THIEME VERLAG KG |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2386102 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Chen, Yuanwei |
| 作者单位 | 1.Chinese Acad Sci, Chengdu Inst Organ Chem, Chengdu 610041, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China |
| 推荐引用方式 GB/T 7714 | Liu, Zhangqin,Shi, Changqing,Chen, Yuanwei. Synthesis of 3-alkyl-1h-quinolin-2-ones via palladium-catalyzed intramolecular cyclization of benzyl halides and alpha,beta-unsaturated amides[J]. Synlett,2008(11):1734-1736. |
| APA | Liu, Zhangqin,Shi, Changqing,&Chen, Yuanwei.(2008).Synthesis of 3-alkyl-1h-quinolin-2-ones via palladium-catalyzed intramolecular cyclization of benzyl halides and alpha,beta-unsaturated amides.Synlett(11),1734-1736. |
| MLA | Liu, Zhangqin,et al."Synthesis of 3-alkyl-1h-quinolin-2-ones via palladium-catalyzed intramolecular cyclization of benzyl halides and alpha,beta-unsaturated amides".Synlett .11(2008):1734-1736. |
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来源：中国科学院大学
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