An organocatalytic approach to the construction of chiral oxazolidinone rings and application in the synthesis of antibiotic linezolid and its analogues
文献类型：期刊论文
| 作者 | Song, Lirong1; Chen, Xiaobei1; Zhang, Shilei1; Zhang, Haoyi1; Li, Ping1; Luo, Guangshun1; Liu, Wenjing1; Duan, Wenhu1,2; Wang, Wei1,3 |
| 刊名 | Organic letters
 |
| 出版日期 | 2008-12-04 |
| 卷号 | 10期号:23页码:5489-5492 |
| ISSN号 | 1523-7060 |
| DOI | 10.1021/ol802333n |
| 通讯作者 | Zhang, shilei(zs1103@yahoo.com.cn) |
| 英文摘要 | An efficient, catalytic asymmetric approach to antibacterial agent linezolid has been developed. the route features organocatalytic, highly enantioselective aldol and beckman rearrangement reactions. the strategy has also been successfully applied for the preparation of new alpha-substituted analogues with high enantio- and diastereoselectivity. |
| WOS关键词 | ASYMMETRIC ALDOL REACTIONS ; ANTIBACTERIAL AGENTS ; ENANTIOSELECTIVE SYNTHESIS ; PROLINE ; DERIVATIVES ; EFFICIENT ; WATER ; IDENTIFICATION ; INFECTIONS ; INHIBITORS |
| WOS研究方向 | Chemistry |
| WOS类目 | Chemistry, Organic |
| 语种 | 英语 |
| WOS记录号 | WOS:000261294300043 |
| 出版者 | AMER CHEMICAL SOC |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2392942 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Zhang, Shilei |
| 作者单位 | 1.E China Univ Sci & Technol, Dept Pharmaceut Sci, Sch Pharm, Shanghai 200237, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai Inst Biol Sci, Grad Sch, Shanghai 201203, Peoples R China 3.Univ New Mexico, Dept Chem & Biol Chem, Albuquerque, NM 87131 USA |
| 推荐引用方式 GB/T 7714 | Song, Lirong,Chen, Xiaobei,Zhang, Shilei,et al. An organocatalytic approach to the construction of chiral oxazolidinone rings and application in the synthesis of antibiotic linezolid and its analogues[J]. Organic letters,2008,10(23):5489-5492. |
| APA | Song, Lirong.,Chen, Xiaobei.,Zhang, Shilei.,Zhang, Haoyi.,Li, Ping.,...&Wang, Wei.(2008).An organocatalytic approach to the construction of chiral oxazolidinone rings and application in the synthesis of antibiotic linezolid and its analogues.Organic letters,10(23),5489-5492. |
| MLA | Song, Lirong,et al."An organocatalytic approach to the construction of chiral oxazolidinone rings and application in the synthesis of antibiotic linezolid and its analogues".Organic letters 10.23(2008):5489-5492. |
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来源：中国科学院大学
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