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Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共98条，第1-10条 帮助

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A novel strategy for treating oncogene-mutated tumors by targeting tumor microenvironment and synergistically enhancing anti-PD-1 immunotherapy 期刊论文  OAI收割
CANCER COMMUNICATIONS, 2024, 页码: 5
作者:  Liu, Yingqiang;  Tong, Linjiang;  Zhang, Mengge;  Zhang, Qi;  Liu, Qiupei
  |  收藏  |  浏览/下载：12/0  |  提交时间：2024/03/13
Discovery of a 1,6-naphthyridin-4-one-based AXL inhibitor with improved pharmacokinetics and enhanced in vivo antitumor efficacy 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 17
作者:  Lan, Yaohan;  Peng, Xia;  Ji, Yinchun;  Su, Yi;  Duan, Wenhu
  |  收藏  |  浏览/下载：8/0  |  提交时间：2024/02/27
Discovery of hematopoietic progenitor kinase 1 inhibitors using machine learning-based screening and free energy perturbation 期刊论文  OAI收割
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2024, 页码: 13
作者:  Feng, Dazhi;  Liu, Bo;  Chen, Zhiwei;  Xu, Jinyi;  Geng, Meiyu
  |  收藏  |  浏览/下载：24/0  |  提交时间：2024/02/27
Preclinical and early clinical studies of a novel compound SYHA1813 that efficiently crosses the blood-brain barrier and exhibits potent activity against glioblastoma 期刊论文  OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4748-4764
作者:  Liu, Yingqiang;  Zhan, Zhengsheng;  Kang, Zhuang;  Li, Mengyuan;  Lv, Yongcong
  |  收藏  |  浏览/下载：9/0  |  提交时间：2024/01/26
Design, synthesis, and STING-agonistic activity of benzo[b]thiophene-2-carboxamide derivatives 期刊论文  OAI收割
MOLECULAR DIVERSITY, 2023, 页码: 10
作者:  Zhou, Rongyao;  Wang, Xiyuan;  Zhang, Deqiang;  Zhan, Zhengsheng;  Duan, Wenhu
  |  收藏  |  浏览/下载：6/0  |  提交时间：2023/12/08
Design, synthesis and pharmacological evaluation of 2,3-dihydrobenzo-furan IRAK4 inhibitors for the treatment of diffuse large B-cell lymphoma 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 256, 页码: 16
作者:  Chen, Yun;  Ning, Yi;  Chen, Zhiwei;  Xue, Yaping;  Wu, Qingyun
  |  收藏  |  浏览/下载：11/0  |  提交时间：2023/10/17
Discovery of 10H-Benzo[b]pyrido[2,3-e][1,4]oxazine AXL Inhibitors via Structure-Based Drug Design Targeting c-Met Kinase 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 15
作者:  Zhan, Zhengsheng;  Ji, Yinchun;  Su, Haixia;  Fang, Chen;  Peng, Xia
  |  收藏  |  浏览/下载：30/0  |  提交时间：2023/04/10
Structural insights into a shared mechanism of human STING activation by a potent agonist and an autoimmune disease-associated mutation 期刊论文  OAI收割
CELL DISCOVERY, 2022, 卷号: 8, 期号: 1, 页码: 17
作者:  Xie, Zuoquan;  Wang, Zhen;  Fan, Fengying;  Zhou, Jinpei;  Hu, Zhaoxue
  |  收藏  |  浏览/下载：21/0  |  提交时间：2023/04/10
Discovery and structure - activity relationship exploration of pyrazolo [1,5-a]pyrimidine derivatives as potent FLT3-ITD inhibitors 期刊论文  OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 48, 页码: 13
作者:  Chen, Yun;  Bai, Gang;  Li, Yan;  Ning, Yi;  Cao, Sufen
  |  收藏  |  浏览/下载：57/0  |  提交时间：2021/12/01
Discovery of pyrrolo[2,3-d]pyrimidine derivatives as potent Axl inhibitors: Design, synthesis and biological evaluation 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 220, 页码: 18
作者:  Xu, Dandan;  Sun, Deqiao;  Wang, Wei;  Peng, Xia;  Zhan, Zhengsheng
  |  收藏  |  浏览/下载：38/0  |  提交时间：2021/08/17