Surface modification of bioactive glasses and preparation of pdlla/bioactive glass composite films
文献类型：期刊论文
| 作者 | Gao, Yuan1,2; Chang, Jiang1 |
| 刊名 | Journal of biomaterials applications
 |
| 出版日期 | 2009-08-01 |
| 卷号 | 24期号:2页码:119-138 |
| 关键词 | Surface modification Composite film Bioactive glass Pdlla Dodecyl alcohol |
| ISSN号 | 0885-3282 |
| DOI | 10.1177/0885328208094265 |
| 通讯作者 | Chang, jiang(jchang@mail.sic.ac.cn) |
| 英文摘要 | In order to improve the homogeneous dispersion of particles in the polymeric matrix, 45s5, mesoporous 58s, and 58s bioactive glasses were surface modified by esterification reactions with dodecyl alcohol at reflux temperature of 260 degrees c (named as m-45s5, m-mesoporous 58s, and m-58s, respectively). the modified particles showed better hydrophobicity and longer time of suspension in organic matrix. the pdlla/bioactive glass composite films were fabricated using surface modified bioactive glass particles through solvent casting-evaporation method. surface morphology, mechanical property, and bioactivity were investigated. the results revealed that the inorganic particle distribution and tensile strength of the composite films with modified bioactive glass particles were significantly improved while great bioactive properties were maintained. scanning electron microscopy (sem) observation illustrated that the modified bioactive glass particles were homogeneously dispersed in the pdlla matrix. the maximum tensile strengths of composite films with modified bioactive glass particles were higher than that of composite films with unmodified bioactive glass particles. the bioactivity of the composite films were evaluated by being soaked in the simulated body fluid (sbf) and the sem observation of the films suggested that the modified composite films were still bioactive in that they could induce the formation of hap on its surface and the distribution of hap was even more homogeneous on the film. the results mentioned above indicated that the surface modification of bioactive glasses with dodecyl alcohol was an effective method to prepare pdlla/bioactive glass composites with enhanced properties. by studying the comparisons of modification effects among the three types of bioactive glasses, we could get the conclusion that the size and morphology of the inorganic particles would greatly affect the modification effects and the properties of composites. |
| WOS关键词 | BONE ; TISSUE ; FABRICATION ; SCAFFOLDS ; CELLS |
| WOS研究方向 | Engineering ; Materials Science |
| WOS类目 | Engineering, Biomedical ; Materials Science, Biomaterials |
| 语种 | 英语 |
| WOS记录号 | WOS:000268877900003 |
| 出版者 | SAGE PUBLICATIONS LTD |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2397270 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Chang, Jiang |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Inst Ceram, Biomat & Tissue Engn Res Ctr, Shanghai 200050, Peoples R China 2.Chinese Acad Sci, Grad Sch, Shanghai 200031, Peoples R China |
| 推荐引用方式 GB/T 7714 | Gao, Yuan,Chang, Jiang. Surface modification of bioactive glasses and preparation of pdlla/bioactive glass composite films[J]. Journal of biomaterials applications,2009,24(2):119-138. |
| APA | Gao, Yuan,&Chang, Jiang.(2009).Surface modification of bioactive glasses and preparation of pdlla/bioactive glass composite films.Journal of biomaterials applications,24(2),119-138. |
| MLA | Gao, Yuan,et al."Surface modification of bioactive glasses and preparation of pdlla/bioactive glass composite films".Journal of biomaterials applications 24.2(2009):119-138. |
入库方式： iSwitch采集
来源：中国科学院大学
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。