中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Synthesis, in vitro hydroxyapatite forming ability, and cytocompatibility of strontium silicate powders

文献类型:期刊论文

作者Zhang, Meili1,2; Zhai, Wanyin1; Lin, Kaili1; Pan, Haobo3; Lu, William3; Chang, Jiang1
刊名Journal of biomedical materials research part b-applied biomaterials
出版日期2010-04-01
卷号93b期号:1页码:252-257
关键词Strontium silicate Hydroxyapatite forming ability Cytocompatibility
ISSN号1552-4973
DOI10.1002/jbm.b.31582
通讯作者Chang, jiang(jchang@mail.sic.ac.cn)
英文摘要Phase-pure strontium silicate (srsio(3)) powders were synthesized by chemical precipitation method. in vitro bioactivity of the powders were evaluated by examining the hydroxyapatite forming ability on their surface soaking simulated body fluid for various periods. the results showed that srsio(3) could induce hydroxy carbonate apatite formation after soaking for 7 days. both l929 and rabbit bone marrow stromal cells (rmscs) were used to test the in vitro cytocompatibility of srsio(3). l929 culture experiment showed that the ionic product of srsio(3) did not exhibit cytotoxicity except at high ion concentrations (si 3.75 mm and sr 0.12 mm). moreover, at certain ion concentrations (si 1.87-0.12 mm and sr 0.12-3.75 x 10(-3) mm), the ionic product of srsio(3) stimulated the proliferation of rmscs. all the results indicated that srsio(3) might be used as a new bioactive material for bone regeneration applications. (c) 2010 wiley periodicals, inc. j biomed mater res part b: appl biomater 93b: 252-257, 2010
WOS关键词BIOACTIVE GLASS DISSOLUTION ; SIMULATED BODY-FLUID ; BONE-FORMATION ; TRICALCIUM PHOSPHATE ; APATITE FORMATION ; IONIC PRODUCTS ; OSTEOBLAST ; CERAMICS ; DIFFERENTIATION ; CALCIUM
WOS研究方向Engineering ; Materials Science
WOS类目Engineering, Biomedical ; Materials Science, Biomaterials
语种英语
WOS记录号WOS:000275796700028
出版者WILEY-LISS
URI标识http://www.irgrid.ac.cn/handle/1471x/2410958
专题中国科学院大学
通讯作者Chang, Jiang
作者单位1.Chinese Acad Sci, Shanghai Inst Ceram, State Key Lab High Performance Ceram & Superfine, Shanghai 200050, Peoples R China
2.Chinese Acad Sci, Grad Sch, Shanghai 200050, Peoples R China
3.Univ Hong Kong, Dept Orthoped & Traumatol, Hong Kong, Hong Kong, Peoples R China
推荐引用方式
GB/T 7714
Zhang, Meili,Zhai, Wanyin,Lin, Kaili,et al. Synthesis, in vitro hydroxyapatite forming ability, and cytocompatibility of strontium silicate powders[J]. Journal of biomedical materials research part b-applied biomaterials,2010,93b(1):252-257.
APA Zhang, Meili,Zhai, Wanyin,Lin, Kaili,Pan, Haobo,Lu, William,&Chang, Jiang.(2010).Synthesis, in vitro hydroxyapatite forming ability, and cytocompatibility of strontium silicate powders.Journal of biomedical materials research part b-applied biomaterials,93b(1),252-257.
MLA Zhang, Meili,et al."Synthesis, in vitro hydroxyapatite forming ability, and cytocompatibility of strontium silicate powders".Journal of biomedical materials research part b-applied biomaterials 93b.1(2010):252-257.

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来源:中国科学院大学

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