Design, synthesis and antitumor activity of a series of novel coumarin-stilbenes hybrids, the 3-arylcoumarins
文献类型：期刊论文
| 作者 | Xiao, Chun Fen1,2; Tao, Li Yang3; Sun, Hong Yi1,2; Wei, Wen1; Chen, Yu1,2; Fu, Li Wu3; Zou, Yong1 |
| 刊名 | Chinese chemical letters
 |
| 出版日期 | 2010-11-01 |
| 卷号 | 21期号:11页码:1295-1298 |
| 关键词 | Perkin reaction 3-arylcoumarin Trans-stilbene Antitumor activity |
| ISSN号 | 1001-8417 |
| DOI | 10.1016/j.cclet.2010.04.034 |
| 通讯作者 | Zou, yong(zou_jinan@163.com) |
| 英文摘要 | A series of novel coumarin-stilbenes hybrids called 3-arylcoumarins were synthesized via perkin reaction and evaluated as potential antitumor agents. the results showed that some compounds exhibited in vitro activity against kb, kv, mcf-7, mcf-7/adr cell lines to some extent. compound 3a showed remarkable effect against kb tumor cells with an ic(50) value of 5.18 mu mol/l. (c) 2010 yong zou. published by elsevier b.v. on behalf of chinese chemical society. all rights reserved. |
| WOS关键词 | IN-VITRO |
| WOS研究方向 | Chemistry |
| WOS类目 | Chemistry, Multidisciplinary |
| 语种 | 英语 |
| WOS记录号 | WOS:000283899700009 |
| 出版者 | ELSEVIER SCIENCE INC |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2415271 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Zou, Yong |
| 作者单位 | 1.Chinese Acad Sci, Guangzhou Inst Chem, Guangzhou 510650, Guangdong, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China 3.Sun Yat Sen Univ, Ctr Canc, Oncol Res Dept, Guangzhou 510060, Guangdong, Peoples R China |
| 推荐引用方式 GB/T 7714 | Xiao, Chun Fen,Tao, Li Yang,Sun, Hong Yi,et al. Design, synthesis and antitumor activity of a series of novel coumarin-stilbenes hybrids, the 3-arylcoumarins[J]. Chinese chemical letters,2010,21(11):1295-1298. |
| APA | Xiao, Chun Fen.,Tao, Li Yang.,Sun, Hong Yi.,Wei, Wen.,Chen, Yu.,...&Zou, Yong.(2010).Design, synthesis and antitumor activity of a series of novel coumarin-stilbenes hybrids, the 3-arylcoumarins.Chinese chemical letters,21(11),1295-1298. |
| MLA | Xiao, Chun Fen,et al."Design, synthesis and antitumor activity of a series of novel coumarin-stilbenes hybrids, the 3-arylcoumarins".Chinese chemical letters 21.11(2010):1295-1298. |
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来源：中国科学院大学
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