Effects of molecular structures on the olfactory responses of phospholipid membranes to four alcohols
文献类型：期刊论文
| 作者 | Zhou, QZ; Yang, YN; Chen, ZK; Sun, A |
| 刊名 | Chemistry and physics of lipids
 |
| 出版日期 | 1998-09-01 |
| 卷号 | 95期号:1页码:1-9 |
| 关键词 | Olfactory sensor Interdigital electrode Hydrocarbon chain Head-group Voltage response |
| ISSN号 | 0009-3084 |
| 通讯作者 | Zhou, qz() |
| 英文摘要 | In order to understand the relationship between phospholipid molecular structures and their olfactory responses to odorants, we designed and synthesized four phosphatidylcholine analogues with different long hydrocarbon (ch) chains and selected three natural phospholipids with different head-groups. by using interdigital electrodes (ies) as olfactory sensors (oss), we measured the responses of the ifs coated with these seven different lipid membranes to four alcohol vapors in a gas flow system. the ifs voltage changes were recorded and the voltage-relative saturate vapor pressure (v-p/p degrees) curves were also plotted. it was found that with a methyl (-ch3) placed at the c-8 position in the 18-carbon chain, the olfactory responses could be improved about ten times and with conjugated double bonds (c=c) in the long chains, the sensitivity could be increased by 3 similar to 4 orders of magnitude. as to head-groups, choline is preferred over ethanolamine and serine in phospholipid structures in terms of high olfactory sensitivity: these results are expected to be useful in further designing and manufacturing lipid-mimicking oss. (c) 1998 elsevier science ireland ltd. all rights reserved. |
| WOS关键词 | LIPID-MEMBRANES ; LIPOSOMES ; ODORANTS ; PACKING ; SENSOR |
| WOS研究方向 | Biochemistry & Molecular Biology ; Biophysics |
| WOS类目 | Biochemistry & Molecular Biology ; Biophysics |
| 语种 | 英语 |
| WOS记录号 | WOS:000076497600001 |
| 出版者 | ELSEVIER SCI IRELAND LTD |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2428620 |
| 专题 | 半导体研究所 |
| 通讯作者 | Zhou, QZ |
| 作者单位 | 1.Peking Univ, Coll Chem & Mol Engn, Beijing 100871, Peoples R China 2.Chinese Acad Sci, Inst Semicond, Beijing 100864, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhou, QZ,Yang, YN,Chen, ZK,et al. Effects of molecular structures on the olfactory responses of phospholipid membranes to four alcohols[J]. Chemistry and physics of lipids,1998,95(1):1-9. |
| APA | Zhou, QZ,Yang, YN,Chen, ZK,&Sun, A.(1998).Effects of molecular structures on the olfactory responses of phospholipid membranes to four alcohols.Chemistry and physics of lipids,95(1),1-9. |
| MLA | Zhou, QZ,et al."Effects of molecular structures on the olfactory responses of phospholipid membranes to four alcohols".Chemistry and physics of lipids 95.1(1998):1-9. |
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来源：半导体研究所
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