Porous morphology, porosity, mechanical properties of poly(alpha-hydroxy acid)-tricalcium phosphate composite scaffolds fabricated by low-temperature deposition
文献类型：期刊论文
| 作者 | Liu, Li; Xiong, Zhuo; Yan, Yongnian; Hu, Yunyu; Zhang, Renji; Wang, Shenguo |
| 刊名 | JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
 |
| 出版日期 | 2007-09-01 |
| 卷号 | 82A期号:3页码:618-629 |
| 关键词 | Tissue Engineering Scaffold Rapid Prototyping Low-temperature Deposition Macrocellular Morphology Microcellular Morphology Porosity Mechanical Properties |
| ISSN号 | 1549-3296 |
| DOI | 10.1002/bjm.a.31177 |
| 英文摘要 | Tissue engineering is expected to construct complicated hominine organs composed of many different types of cells. One of the key points is the accurate controlling of scaffold material and porous morphology point by point. A new direct rapid prototyping process called low-temperature deposition manufacturing (LDM) was proposed to fabricate scaffolds. The new process integrated extrusion/jetting and phase separation and therefore could fabricate scaffolds with hierarchical porous structures creating a wonderful environment for the growth of new tissue. The interconnected computer-designed macropores allow cells in the new tissue to grow throughout the scaffold. Also, the parameter-controlled micropores let nutrition in and metabolic wastes out. The macrocellular morphology, microcellular morphology, porosity, and mechanical properties of the poly(alpha-hydroxy acid)-TCP composite scaffolds prepared by the proposed method are investigated. These scaffolds with high controllability would potentially play an important role in tissue engineering. LDM could also be combined with multinozzle deposition or cell deposition to exactly control materials or cells point by point. This might bring a breakthrough to the engineered fabrication of complicated organs. (C) 2007 Wiley Periodicals, Inc. |
| 语种 | 英语 |
| WOS记录号 | WOS:000248693100011 |
| 出版者 | WILEY-LISS |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/61815]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Xiong, Zhuo |
| 作者单位 | 1.Tsing Hua Univ, Dept Mech Engn, Ctr Laser Rapid Forming, Beijing 100084, Peoples R China 2.Tsing Hua Univ, Inst Life Sci & Med, Ctr Organism Mfg Engn, Beijing 100084, Peoples R China 3.Fourth Mil Med Univ, Xijing Hosp, Dept Orthopaed & Traumatol, Xian 710032, Peoples R China 4.Chinese Acad Sci, Inst Chem, Beijing 100080, Peoples R China |
| 推荐引用方式 GB/T 7714 | Liu, Li,Xiong, Zhuo,Yan, Yongnian,et al. Porous morphology, porosity, mechanical properties of poly(alpha-hydroxy acid)-tricalcium phosphate composite scaffolds fabricated by low-temperature deposition[J]. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A,2007,82A(3):618-629. |
| APA | Liu, Li,Xiong, Zhuo,Yan, Yongnian,Hu, Yunyu,Zhang, Renji,&Wang, Shenguo.(2007).Porous morphology, porosity, mechanical properties of poly(alpha-hydroxy acid)-tricalcium phosphate composite scaffolds fabricated by low-temperature deposition.JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A,82A(3),618-629. |
| MLA | Liu, Li,et al."Porous morphology, porosity, mechanical properties of poly(alpha-hydroxy acid)-tricalcium phosphate composite scaffolds fabricated by low-temperature deposition".JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A 82A.3(2007):618-629. |
入库方式： OAI收割
来源：化学研究所
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